900 retinoblastoma survivors join landmark study to uncover Long-Term health secrets

NCT ID NCT03932786

Recruiting now Knowledge-focused Sponsor: Vanderbilt-Ingram Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study follows 900 children who were treated for retinoblastoma, a rare eye cancer, to track their long-term health. Researchers will collect vision tests, tissue and saliva samples, and questionnaires from patients and their siblings. The goal is to learn more about what causes the disease, identify late effects of treatment, and find the best therapies for the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand the long-term effects of retinoblastoma treatments and improve future care.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test a new therapy, and results may take years to influence clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intraocular retinoblastoma retinoblastoma unilateral retinoblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIOLOGICAL SIBLING CANCER SURVIVOR INTRAOCULAR RETINOBLASTOMA RETINOBLASTOMA UNILATERAL RETINOBLASTOMA

Contacts and locations

Locations

Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Children's Hospital of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Cincinnati Children's Hospital Medical Center
RECRUITING

Cincinnati, Ohio, 45229, United States
Lurie Children's Hospital
RECRUITING

Chicago, Illinois, 60611, United States
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Texas Childeren's Hospital
RECRUITING

Houston, Texas, 77030, United States
The Hosptial for Sick Children
RECRUITING

Toronto, Canada
University of Illinois, Chicago
RECRUITING

Chicago, Illinois, 60612, United States
University of Minnesoa
RECRUITING

Minneapolis, Minnesota, 55455, United States
Vanderbilt-Ingram Cancer Center
RECRUITING

Nashville, Tennessee, 37232, United States
Washington School of Medicine at St. Louis
RECRUITING

St Louis, Missouri, 63110, United States

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