Vanderbilt-ingram Cancer Center

This phase II trial is testing whether a combination of two drugs, rigosertib and pembrolizumab, can help people with advanced melanoma that no longer responds to standard immunotherapy. The study involves 7 participants with unresectable or metastatic melanoma. The goal is to se…

This study is testing a combined biomarker model (CBM) that uses a blood test and CT scan features to better classify lung nodules as benign or cancerous. Researchers will follow 103 adults with intermediate-risk nodules to see if the model can reduce unnecessary invasive procedu…

This study tests whether an artificial intelligence (AI) tool called the Virtual Nodule Clinic can help doctors better manage lung nodules that are not clearly cancerous or benign. The AI analyzes CT scans and patient information to estimate the risk of cancer. The goal is to see…

This study follows 45 uninsured current or former heavy smokers to find early signs of lung cancer. Researchers collect samples like sputum, blood, and urine, and perform CT scans to test new detection methods. The goal is to improve early diagnosis in a group that often misses o…

The IMPACT Study is testing two online tools—GeneSHARE and LivingLabReport—to help people with inherited cancer gene variants share their results with family members and follow cancer screening guidelines. The study involves 720 adults who have a genetic variant linked to cancers…