New imaging agent aims to spot hidden cancer in neck lymph nodes
NCT ID NCT05901545
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests whether a radioactive imaging agent called 111In-panitumumab can help find cancer that has spread to lymph nodes in people with head and neck cancer. The agent binds to a protein common on cancer cells and lights up on a special scan. About 30 participants will receive the agent before surgery, and doctors will compare the scan results with what they find during the operation. The main goal is to check safety and see if the agent improves detection of cancerous lymph nodes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Indium In 111 panitumumab (a radioactive imaging agent)
- What this could lead to
- If successful, this could improve the accuracy of detecting cancer spread to lymph nodes, helping surgeons remove the right nodes and potentially improving survival outcomes.
- What could go wrong
- This is an early phase I trial with only 30 participants, so it is too soon to know if the imaging agent works better than current methods. There may be side effects from the radioactive substance or the antibody.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Vanderbilt University/Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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