Cancer Institute And Hospital, Chinese Academy Of Medical Sciences

This study tests whether adding the immunotherapy drug toripalimab to standard chemotherapy and radiation can help people with large, locally advanced non-small cell lung cancer. The trial enrolls 50 adults aged 18-75 with tumors at least 5 cm wide or lymph nodes at least 2 cm. T…

This study tests a combination of three drugs (orelabrutinib, zuberitamab, and chemotherapy) in 65 adults with untreated marginal zone lymphoma, a slow-growing blood cancer. The goal is to see if the treatment can make all signs of cancer disappear and keep it away for at least 2…

This study looks at whether giving extra radiation to the internal mammary lymph nodes after mastectomy can help prevent breast cancer from coming back. It involves 2,400 high-risk patients who have had surgery. The goal is to see if this additional treatment improves how long pa…

This study tests a three-drug combination (selinexor, thalidomide, and dexamethasone) in 40 adults with Langerhans cell histiocytosis that did not improve or came back after standard treatment. The goal is to see if the regimen can control the disease and delay progression. Parti…

This study tests a shorter, more intense radiation schedule (hypofractionation) for people with thymic tumors who have had the tumor completely removed. The goal is to see if this approach can prevent the tumor from returning while keeping side effects low. About 50 adults with s…

This study tests a shorter, more targeted radiation therapy (accelerated partial breast irradiation) given after breast-conserving surgery in people with early-stage breast cancer. The goal is to see if this approach controls cancer recurrence and reduces side effects compared to…

This study tests whether adding the drug toripalimab to standard chemoradiotherapy helps people with high-risk, advanced cervical cancer live longer without the cancer growing. About 57 adults with stage III-IVA cervical cancer who haven't had prior treatment will receive toripal…

This study tests a combination of the drug glofitamab with chemotherapy (GemOx) in 40 adults with a type of blood cancer called diffuse large B-cell lymphoma that did not respond to initial treatment. The goal is to see if this combo can make tumors disappear completely for at le…

This study enrolls 4,000 people with bladder cancer to see if artificial intelligence can accurately predict HER2 protein levels using MRI scans and tissue samples. The goal is to create a fast, non-invasive tool that helps doctors decide on targeted therapy without needing extra…

This study follows 138 people who had surgery for esophageal cancer to see how often they experience reflux afterward. Researchers use a simple test called PEPTEST to measure stomach acid in saliva before surgery, at discharge, and 1, 3, and 6 months later. The goal is to find pa…

This study reviews medical records from 300 people with advanced stomach or gastroesophageal junction cancer. Researchers want to see which treatments given before and after surgery help people live longer and whether tumor shrinkage affects survival. No new drugs or procedures a…

This study looks back at medical records of 10,000 people with non-small cell lung cancer who received immunotherapy before surgery. Researchers want to find out which follow-up treatments (like more immunotherapy or chemo) work best to help patients live longer and prevent cance…

This study looks at whether tracking tumor DNA in the blood (ctDNA) can help predict how well treatment works for people with B-cell non-Hodgkin lymphoma. Researchers will collect blood samples from 60 patients before and during treatment to see if changes in ctDNA levels match w…