New hope for rare blood disease: drug cocktail targets stubborn cases

NCT ID NCT07204041

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 30 times

Summary

This study tests a three-drug combination (selinexor, thalidomide, and dexamethasone) in 40 adults with Langerhans cell histiocytosis that did not improve or came back after standard treatment. The goal is to see if the regimen can control the disease and delay progression. Participants will be followed for side effects and overall survival.

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Contacts and locations

Locations

  • Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, beijing,

    Beijing, China

Conditions

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