LANGERHANS CELL HISTIOCYTOSIS (LCH)
Clinical trials for LANGERHANS CELL HISTIOCYTOSIS (LCH) explained in plain language.
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New pill could replace chemo for kids with rare bone disorder
Disease control Recruiting nowThis study tests a new daily pill, luvometinib, in children aged 0-18 with Langerhans cell histiocytosis (LCH) affecting bones. LCH is a rare disease where immune cells grow abnormally, often requiring chemotherapy. The pill targets a key cell pathway to control the disease and p…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: NA • Sponsor: West China Second University Hospital • Aim: Disease control
Last updated May 17, 2026 03:57 UTC
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New combo therapy aims to beat tough childhood Cancer-Like disease
Disease control Recruiting nowThis study tests whether adding a targeted drug called luvometinib to standard chemotherapy works better than chemotherapy alone for children with severe multisystem Langerhans cell histiocytosis (LCH). LCH is a rare immune cell disorder that can damage multiple organs and often …
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: NA • Sponsor: West China Second University Hospital • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New drug shows promise for rare immune diseases
Disease control Recruiting nowThis study tests a drug called mirdametinib in people with histiocytic disorders, including Langerhans cell histiocytosis (LCH). The goal is to see if it works better and has fewer side effects than current treatments. About 40 participants aged 2 and older will take the drug for…
Matched conditions: LANGERHANS CELL HISTIOCYTOSIS (LCH)
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated May 07, 2026 18:42 UTC