Old drug, new hope: lenalidomide takes on rare histiocyte disorders

NCT ID NCT02523040

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This study tests the chemotherapy drug lenalidomide in 12 adults with one of three rare diseases where immune cells grow out of control: Langerhans cell histiocytosis, Erdheim-Chester disease, or histiocytic sarcoma. The main goal is to see how many people have their disease shrink or disappear. This is a phase 2 trial, meaning the drug is already known to be safe, and researchers are checking how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.