Scientists hunt for genetic clues in rare blood disorders
NCT ID NCT05028621
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at the genetic makeup of rare blood diseases like Castleman disease and Langerhans cell histiocytosis. Researchers will analyze blood or tissue samples from 135 participants to find genetic changes that could be targeted by existing or experimental therapies. The goal is to better understand these disorders and open doors to personalized treatment options.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could identify genetic targets for new treatments in rare blood diseases.
What could go wrong
The study is exploratory and currently suspended, so results may be delayed or not lead to direct treatments. It is small and early-stage.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cleveland Clinic, Case Comprehensive Cancer Center
Cleveland, Ohio, 44106-5065, United States