New combo therapy aims to wipe out lymphoma without prior treatment

NCT ID NCT07480863

First seen Mar 21, 2026 · Last updated May 17, 2026 · Updated 8 times

Summary

This study tests a combination of three drugs (orelabrutinib, zuberitamab, and chemotherapy) in 65 adults with untreated marginal zone lymphoma, a slow-growing blood cancer. The goal is to see if the treatment can make all signs of cancer disappear and keep it away for at least 24 months. Participants must be 18 or older, in good general health, and have measurable tumors.

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Contacts and locations

Locations

  • Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, beijing,

    Beijing, China

Conditions

Explore the condition pages connected to this study.