New hope for patients out of options: experimental drug enters first human trials

NCT ID NCT03547115

Summary

This early-stage study tested a new drug called voruciclib, both alone and combined with another drug (venetoclax), in adults with advanced blood cancers like leukemia and lymphoma. The main goal was to find safe dosage levels and see if the treatment showed any early signs of helping patients whose cancers had returned or stopped responding to standard therapies. The trial enrolled 84 participants and focused primarily on monitoring side effects.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University

    Durham, North Carolina, 27705, United States

  • Froedtert Hospital & the Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • MD Anderson

    Houston, Texas, 77030, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • New York University

    New York, New York, 10016, United States

  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Swedish Cancer Institute

    Seattle, Washington, 98104, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Virginia

    Charlottesville, Virginia, 22903, United States

Conditions

Explore the condition pages connected to this study.