CAR-T therapy Follow-Up study shows no new safety surprises

NCT ID NCT04488354

Completed Knowledge-focused Sponsor: Calibr, a division of Scripps Research Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 16 people who had already received a special immune cell treatment (CLBR001 CAR-T) for various types of B-cell blood cancers like lymphoma and leukemia. The goal was to check for any new or long-term side effects that might appear months or years after treatment. Researchers also looked at how well the cancer was controlled over time. This was a safety-focused follow-up, not a test of a new treatment.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia B-cell neoplasm Burkitt lymphoma diffuse large B-cell lymphoma follicular lymphoma hematopoietic and lymphoid system neoplasm Lymphoma, B-Cell, Marginal Zone lymphoplasmacytic lymphoma mantle cell lymphoma marginal zone lymphoma neoplasm primary mediastinal large B-cell lymphoma relapsed/refractory diffuse large B-cell lymphoma Waldenstrom macroglobulinemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BURKITT LYMPHOMA CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) DIFFUSE-LARGE B-CELL LYMPHOMA (DLBCL) FOLLICULAR LYMPHOMA (FL) LYMPHOPLASMACYTIC LYMPHOMA MANTLE CELL LYMPHOMA (MCL) MARGINAL ZONE LYMPHOMA (MZL) PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA RELAPSED/REFRACTORY B-CELL LYMPHOMAS SMALL LYMPHOCYTIC LYMPHOMA (SLL) TRANSFORMED FOLLICULAR LYMPHOMA WALDENSTROM MACROGLOBULINEMIA

Contacts and locations

Locations

City of Hope National Medical Center

Duarte, California, 91010, United States
Masonic Cancer Center, University of Minnesota

Minneapolis, Minnesota, 55455, United States
Sarah Cannon Research Institute - Tennessee Oncology

Nashville, Tennessee, 37203, United States
Sarah Cannon Research Institute - Texas Transplant Institute

San Antonio, Texas, 78229, United States
University of California at San Diego

San Diego, California, 92093, United States
University of Chicago

Chicago, Illinois, 60637, United States
Wake Forest Baptist Health

Winston-Salem, North Carolina, 27157, United States
Weill Cornell Medical College - New York Presbyterian Hospital

New York, New York, 10065, United States

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