New drug trial hopes to shrink Hard-to-Treat pancreatic tumors

NCT ID NCT07561463

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tests a drug called sacituzumab tirumotecan in 30 people with advanced pancreatic cancer that has worsened after at least one prior treatment. The drug is given by IV every two weeks. The main goal is to see if it can shrink tumors, and researchers will also track how long the effect lasts and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sacituzumab tirumotecan (a drug given by IV every 2 weeks)
What this could lead to
If it works, this could offer a new treatment option for people with advanced pancreatic cancer who have run out of standard therapies.
What could go wrong
This is a small, early-phase trial with only 30 people, so results may not apply to everyone. The drug may cause side effects or fail to shrink tumors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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