New cell therapy aims to train immune system against hard-to-treat cancers

NCT ID NCT07396090

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early study tests a new treatment called CAT-101, which uses a patient's own immune cells (dendritic cells) loaded with a cancer protein (mKRAS) to help the body fight tumors. It is for people with advanced pancreatic cancer or other solid tumors that have a specific KRAS mutation. The treatment is given alone or with another drug (tislelizumab) that boosts the immune response. The main goals are to check safety and see if the treatment shrinks tumors.

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Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma neoplasm pancreatic adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.