Immunotherapy before surgery could boost cervical cancer outcomes
NCT ID NCT07088731
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This Phase 2 trial compares two approaches for locally advanced cervical cancer: standard chemoradiotherapy versus a newer strategy of chemotherapy plus immunotherapy (sintilimab) before surgery. The study will enroll 180 people and track how long they live without the cancer getting worse over two years. The goal is to see if adding immunotherapy before surgery improves results compared to the current standard treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Nab-paclitaxel, cisplatin, and sintilimab (a type of immunotherapy)
- What this could lead to
- If successful, this could show that adding immunotherapy before surgery improves outcomes for locally advanced cervical cancer, potentially offering a new treatment option.
- What could go wrong
- This is a Phase 2 trial, so results are still early and may not confirm benefit. Adding immunotherapy can cause immune-related side effects, and the study is small and single-center, limiting generalizability.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Gynecological Oncology
Beijing, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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