Radiation may tame Treatment-Resistant breast cancer
NCT ID NCT07672743
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests whether high-dose radiation can control tumors in people with locally advanced or recurrent metastatic breast cancer that has not responded to systemic therapy. Participants receive radical-dose radiotherapy, and those with large tumors (5 cm or more) may get a special technique called spatially fractionated radiation therapy. The goal is to see if this approach can shrink or stabilize tumors when other treatments have failed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radiation therapy (radical dose radiotherapy, including spatially fractionated radiation therapy)
- What this could lead to
- If successful, this approach could offer a way to control locally advanced or recurrent breast cancer that has stopped responding to standard treatments.
- What could go wrong
- This is a small, early-phase study with only 29 participants, so results may not apply broadly. Radiation can cause side effects like skin irritation, fatigue, or damage to nearby tissues.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cancer Hospital, Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, 100021, China
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