New hope for esophageal cancer patients after standard treatment fails

NCT ID NCT07530549

First seen Apr 20, 2026 · Last updated May 14, 2026 · Updated 3 times

Summary

This study tests whether a combination of two immunotherapy drugs (Iparomlimab and Tuvonralimab) plus chemoradiotherapy can help people with locally advanced esophageal cancer whose prior chemo-immunotherapy did not work. About 40 adults aged 18-75 will receive the treatment, and researchers will track how long they live without the cancer growing or returning, as well as side effects. The goal is to see if this approach can improve survival and possibly allow surgery later.

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