STAGE IV LUNG CANCER AJCC V8
Clinical trials for STAGE IV LUNG CANCER AJCC V8 explained in plain language.
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New drug duo takes on tough lung cancer
Disease control OngoingThis early-stage trial tests the safety and best dose of a new drug called minnelide when given with the standard drug osimertinib for people with advanced non-small cell lung cancer that has an EGFR mutation. The study involves about 8 adults whose cancer has spread or cannot be…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 29, 2026 00:51 UTC
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Heat vs. scalpel: new study tests which lung tumor treatment works best
Disease control OngoingThis study compares two treatments for lung tumors: microwave ablation (using heat to kill cancer cells) and surgical wedge resection (removing a small piece of lung). It includes 74 adults with non-small cell lung cancer, sarcoma, or colorectal cancer that has spread to the lung…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 29, 2026 00:51 UTC
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One-and-Done radiation: new hope for lung cancer patients after surgery?
Disease control OngoingThis study looks at whether a single, precise dose of radiation given after surgery for non-small cell lung cancer is safe and effective. Standard radiation requires many small doses over weeks, which can damage healthy lung tissue. The trial involves 50 adults who had lung cance…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Apr 29, 2026 00:49 UTC
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New combo therapy aims to outdo chemo for advanced lung cancer patients
Disease control OngoingThis phase 3 trial tests whether a combination of two drugs (ramucirumab and pembrolizumab) works better than standard chemotherapy for people with stage IV or recurrent non-small cell lung cancer who have already been treated with immunotherapy. About 838 participants will be ra…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC
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Experimental drug combo targets brain tumors from lung cancer
Symptom relief OngoingThis early-phase trial is testing the safety and best dose of a drug called berzosertib when given together with whole brain radiation therapy. It includes 15 adults with lung cancer that has spread to the brain. The goal is to find out if adding the drug to radiation is safe and…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Symptom relief
Last updated Apr 29, 2026 00:52 UTC
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Nurse-Led program aims to ease fear in advanced cancer patients
Symptom relief OngoingThis study tests a nurse-led program designed to help people with advanced lung or gynecologic cancer cope with fears about their future. The program teaches practical ways to manage worry and unhelpful thoughts. Researchers want to see if the program is practical and helpful for…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
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New hope for cancer patients losing appetite: drug shows promise in early trial
Symptom relief OngoingThis study looks at whether a drug called anamorelin can help improve appetite and stop weight loss in people with advanced non-small cell lung cancer who have lost their appetite and weight. About 25 participants will take either the drug or a placebo daily and share their exper…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
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Blood test may help cancer patients avoid nerve damage from chemo
Knowledge-focused TerminatedThis study looks at whether doctors can consistently measure the amount of paclitaxel (a chemotherapy drug) in the blood of cancer patients. The goal is to see if this information can help adjust doses to kill cancer while reducing nerve damage, a common side effect. About 22 adu…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC