STAGE IV LUNG CANCER AJCC V8
Clinical trials for STAGE IV LUNG CANCER AJCC V8 explained in plain language.
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New drug combo targets brain metastases in advanced cancers
Disease control TerminatedThis study tested a combination of two drugs, bintrafusp alfa and pimasertib, in people whose cancer had spread to the brain. The goal was to find the safest dose and see if the treatment could slow or stop the cancer from growing. The trial was stopped early after enrolling only…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 16, 2026 12:55 UTC
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Promising cancer combo trial halted early
Disease control TerminatedThis study tested a new drug (BMS-986218) plus nivolumab and targeted radiation in people with advanced solid tumors that had spread. The goal was to see if this combination could help the immune system fight cancer better. Only 13 people took part before the study was stopped ea…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 16, 2026 12:49 UTC
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Personalized lung cancer trial halted early, but shows promise
Disease control TerminatedThis study tested whether matching specific targeted drugs to the genetic changes in a person's ALK-positive lung cancer could improve treatment. It included 10 adults with advanced non-small cell lung cancer that had already been treated. The trial was stopped early due to low e…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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Experimental cocktail aims to reboot immune attack on tough cancers
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combo could shrink tumors or con…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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Lung cancer combo trial halted early – what we know
Disease control TerminatedThis study tested whether adding the immunotherapy drug bintrafusp alfa to standard chemotherapy (docetaxel) could help people with advanced non-small cell lung cancer whose disease had worsened after prior treatment. Only 10 participants were enrolled before the trial was stoppe…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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New combo therapy for tough lung cancer shows early promise
Disease control TerminatedThis early-phase study tested a combination of two immunotherapy drugs (atezolizumab and varlilumab) plus radiation in 16 people with advanced non-small cell lung cancer that had spread and was no longer responding to standard treatments. The main goal was to check safety and sid…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 09, 2026 12:07 UTC
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Brain radiation showdown: whole brain vs. targeted beams for recurrent tumors
Disease control TerminatedThis study looked at two radiation approaches for people whose cancer has spread to the brain and come back after initial treatment. One approach uses targeted radiation only on the new spots, while the other uses whole-brain radiation that tries to protect memory areas and inclu…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 09, 2026 12:07 UTC
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Can meal timing protect your brain during cancer treatment?
Symptom relief TerminatedThis study tested a text-message-based diet program called Txt4fasting for people with breast or lung cancer that spread to the brain. The goal was to see if eating only during certain hours could reduce thinking and memory problems after radiation. Only 1 person enrolled before …
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated Jun 12, 2026 12:05 UTC