Lung cancer combo trial halted early – what we know
NCT ID NCT04396535
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding bintrafusp alfa (an immunotherapy) to standard chemotherapy (docetaxel) helps people with advanced non-small cell lung cancer who have already tried other treatments. Only 10 people took part before the study was stopped early. The goal was to see if the combination could slow cancer growth better than chemo alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Docetaxel and bintrafusp alfa
- What this could lead to
- If successful, this combination could offer a new treatment option for advanced lung cancer patients who have already tried standard therapies.
- What could go wrong
- The trial was terminated early with only 10 participants, so results are very limited. It is unclear if the combination is better than docetaxel alone, and side effects from both drugs can be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
-
Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Wheat germ supplement studied for immune boost in advanced cancer
- New imaging agent may help doctors see which lung tumors are still growing during immunotherapy