New imaging agent may help doctors see which lung tumors are still growing during immunotherapy
NCT ID NCT07619599
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial will test a new PET imaging agent called 64Cu-DOTA-pembrolizumab in 6 people with stage IV non-small cell lung cancer who are already on the immunotherapy drug pembrolizumab. The goal is to see if the imaging agent can safely tell the difference between tumors that are still growing and those that are stable. Participants will also receive low-dose radiation to some tumors to see how that affects the imaging results.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
64Cu-DOTA-pembrolizumab (a radioactive imaging agent)
What this could lead to
If successful, this could give doctors a better way to see which tumors are still growing during immunotherapy, helping guide treatment decisions.
What could go wrong
This is a very early, small pilot study with only 6 people. It is designed to test safety and imaging ability, not to change treatment yet. The imaging agent may not clearly distinguish tumor types.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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