METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Clinical trials for METASTATIC MALIGNANT NEOPLASM IN THE BRAIN explained in plain language.
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Brain cancer trial tests if timing of radiation improves survival
Disease control Recruiting nowThis study aims to find out if giving a precise, high-dose radiation treatment before surgery works better than giving it after surgery for brain tumors that have spread from other cancers. It will enroll 140 adults with a single brain tumor that surgeons can remove. The main goa…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Radiation showdown: one big dose vs. several smaller ones for brain tumors
Disease control Recruiting nowThis study aims to find out which type of focused radiation therapy works better for patients with cancer that has spread to the brain. It compares a single, high-dose treatment to a series of smaller doses spread out over time. Researchers want to see which method better control…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New vaccine trial aims to train immune system to fight breast cancer in the brain
Disease control Recruiting nowThis study is testing a two-part treatment for breast cancer that has spread to the brain. Patients receive a personalized vaccine made from their own immune cells, combined with an immunotherapy drug called pembrolizumab. The goal is to see if this combination can shrink brain t…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Brain cancer radiation showdown: one big dose vs. three smaller ones
Disease control Recruiting nowThis study aims to find the best radiation method for treating cancer that has spread to the brain. It compares giving one large radiation dose versus spreading the same total radiation over three smaller treatments. Researchers want to see which approach better controls the brai…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Can a common amino acid boost brain cancer treatment?
Disease control Recruiting nowThis early study is testing whether giving patients the amino acid arginine alongside standard whole-brain radiation therapy is safe and might make the radiation work better against cancer that has spread to the brain. Researchers are comparing whether taking arginine by mouth or…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: EARLY_PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Donor immune cells target deadly brain tumors in new cancer trial
Disease control Recruiting nowThis early-stage trial is testing a new combination treatment for melanoma that has spread to the brain. Researchers are giving patients immune cells from a universal donor (called NK cells) along with a standard chemotherapy drug (temozolomide). The study aims to find the safest…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1, PHASE2 • Sponsor: Kari Kendra • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Memory-Sparing brain radiation trial seeks to protect thinking skills
Disease control Recruiting nowThis study compares two radiation treatments for patients whose small cell lung cancer has spread to the brain. One method targets only the tumors with high precision, while the other treats the whole brain but avoids the memory center. The main goal is to see which approach bett…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Brain battle: two drug cocktails face off against deadly melanoma spread
Disease control Recruiting nowThis trial is testing which of two drug combinations works better for people with advanced melanoma that has spread to the brain. One group gets three drugs (encorafenib, binimetinib, nivolumab), while the other gets two drugs (ipilimumab, nivolumab). The main goal is to see whic…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Race against time: does radiation before surgery better protect the brain?
Disease control Recruiting nowThis study is testing whether giving a single, focused dose of radiation before surgery is better than giving it after surgery for patients with cancer that has spread to the brain. The main goal is to see which timing better prevents the cancer from spreading to the brain's lini…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Can a heart pill shield cancer patients from Treatment's hidden danger?
Disease control Recruiting nowThis study aims to protect the hearts of people with advanced HER2-positive breast cancer who are receiving a specific treatment (trastuzumab) that can sometimes damage the heart. It is observing nearly 500 patients to see how common heart problems are and testing if a common hea…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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New brain scan could predict cancer treatment success
Diagnosis Recruiting nowThis study is testing a new type of PET/MRI scan to see if it can help doctors better understand and predict how well a standard breast cancer treatment will work when the cancer has spread to the brain. Researchers will give the scan to 10 women with this specific type of advanc…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE4 • Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated Mar 30, 2026 14:33 UTC
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New MRI tech aims to solve critical brain cancer puzzle
Diagnosis Recruiting nowThis study is testing two new types of MRI scans to see if they can better tell the difference between a brain tumor that has grown back and harmless scar tissue caused by past radiation treatment. Currently, standard scans often look the same, making it hard for doctors to decid…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Diagnosis
Last updated Mar 30, 2026 14:31 UTC
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New brain scan combo aims for sharper diagnosis
Diagnosis Recruiting nowThis study is testing if using two different contrast agents (gadolinium and ferumoxytol) during a single MRI scan can improve the detection and diagnosis of brain abnormalities, including tumors and metastases. It will involve 150 participants who have neurological symptoms or k…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Diagnosis
Last updated Mar 23, 2026 15:15 UTC
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Brain cancer patients rate telemedicine vs In-Person care
Knowledge-focused Recruiting nowThis study asks brain cancer patients about their experiences with telemedicine versus in-person doctor visits. Researchers want to understand if patients feel they receive the same quality of care through video appointments. The study involves 200 patients completing surveys and…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Tiny catheter in brain surgery could unlock secrets of tumors
Knowledge-focused Recruiting nowThis study is testing a tiny catheter placed during brain surgery to collect fluid from the tumor area. The goal is to find chemical markers in the fluid that could help doctors better understand, diagnose, and monitor brain tumors in the future. The procedure is done during a pa…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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New brain mapping aims to protect speech and movement during tumor surgery
Knowledge-focused Recruiting nowThis study is testing a brain mapping technique called electrocorticography (ECoG) during surgery to remove brain tumors. The goal is to see if this method can better identify the brain areas responsible for movement and speech, helping surgeons avoid damaging them. Researchers w…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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New scan aims to see immune cells inside brain tumors
Knowledge-focused Recruiting nowThis early-phase study is testing whether a new radioactive tracer, called Zr-89 crefmirlimab berdoxam, can help doctors see immune cells inside brain tumors using a PET scan. The goal is to see if this non-invasive scan can accurately show where immune cells are active, which co…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC