METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Clinical trials for METASTATIC MALIGNANT NEOPLASM IN THE BRAIN explained in plain language.
Never miss a new study
Get alerted when new METASTATIC MALIGNANT NEOPLASM IN THE BRAIN trials appear
Sign up with your email to follow new studies for METASTATIC MALIGNANT NEOPLASM IN THE BRAIN, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
By submitting, you agree to our Terms of use
-
New radiation approach may protect memory in lung cancer patients with brain tumors
Disease control Recruiting nowThis study compares two types of radiation for people with small cell lung cancer that has spread to the brain. One method uses a precise, high-dose beam to each tumor, while the other treats the whole brain but avoids the memory center. The goal is to see which approach better p…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 17, 2026 03:16 UTC
-
Timing of brain radiation could change outcomes for cancer patients
Disease control Recruiting nowThis study looks at whether giving focused radiation before or after surgery works better for people with cancer that has spread to the brain. About 140 adults who need surgery for a brain tumor will be randomly assigned to receive stereotactic radiosurgery either before or after…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 17, 2026 03:08 UTC
-
New vaccine-immunotherapy combo targets breast cancer brain metastases
Disease control Recruiting nowThis study tests a combination of a dendritic cell vaccine (which trains the immune system to attack cancer) and pembrolizumab (an immunotherapy drug) in people with breast cancer that has spread to the brain. The goal is to see if this treatment can shrink brain tumors. The stud…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
-
Donor immune cells take on brain melanoma in new trial
Disease control Recruiting nowThis study tests a new treatment for advanced melanoma that has spread to the brain. It combines chemotherapy (temozolomide) with specially grown immune cells from a healthy donor (called NK cells). The goal is to see if this combination is safe and can shrink brain tumors. About…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1, PHASE2 • Sponsor: Kari Kendra • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
-
New hope for brain metastases: Two-Drug combo vs Three-Drug combo in melanoma trial
Disease control Recruiting nowThis study tests two different drug combinations in people with BRAF-V600 mutant melanoma that has spread to the brain. One group gets a three-drug mix (encorafenib, binimetinib, and nivolumab), the other gets two immunotherapy drugs (ipilimumab and nivolumab). The goal is to see…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
-
Timing of radiation may improve brain metastasis treatment
Disease control Recruiting nowThis study tests whether giving focused radiation before surgery for brain metastases works better than giving it after surgery. The goal is to reduce the chance of cancer spreading in the brain lining and improve local control. About 180 adults with brain metastases will be rand…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 06, 2026 16:01 UTC
-
Double-Dye MRI could sharpen brain scans
Diagnosis Recruiting nowThis study tests whether using two contrast agents (gadolinium and ferumoxytol) in one MRI session can improve the detection of brain abnormalities like tumors or nerve disorders. About 150 people with neurological symptoms or brain lesions will be scanned. The goal is to see if …
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Diagnosis
Last updated May 15, 2026 11:55 UTC
-
New scan could reveal hidden brain tumors in breast cancer patients
Diagnosis Recruiting nowThis study tests a special PET/MRI scan that uses a radioactive tracer to find HER2-positive breast cancer that has spread to the brain. Researchers want to see if the scan can show which brain tumors will respond to a standard chemotherapy drug. About 10 women with metastatic br…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE4 • Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated May 13, 2026 16:04 UTC
-
New MRI scans aim to solve a dangerous brain mystery
Diagnosis Recruiting nowThis study tests two advanced MRI techniques to better tell apart brain tumors that have come back from tissue damage caused by radiation therapy. About 42 adults with brain metastases will be scanned before surgery or radiation. The goal is to help doctors choose the right treat…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Diagnosis
Last updated May 06, 2026 16:15 UTC
-
Brain tumor radiation showdown: one big dose or three smaller ones?
Symptom relief Recruiting nowThis study tests whether giving radiation in three smaller doses (fractionated SRS) is better than a single large dose (standard SRS) for treating cancer that has spread to the brain. About 269 adults with certain cancers (like lung, breast, or melanoma) will be enrolled. The goa…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 17, 2026 03:17 UTC
-
One shot or several? trial tests best radiation for brain tumors
Symptom relief Recruiting nowThis study looks at two ways to deliver precise radiation to brain tumors that have spread from other cancers. One method gives all the radiation in a single session, while the other spreads it over several sessions. The goal is to find out which approach better controls the tumo…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 11, 2026 20:41 UTC
-
New Brain-Mapping grid could save speech and movement during surgery
Knowledge-focused Recruiting nowThis study tests a new, high-definition brain-mapping grid during surgery for brain tumors. The goal is to see if it can better identify areas controlling movement and speech, helping surgeons avoid damaging them. About 75 adults with brain tumors near these critical areas will t…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:12 UTC
-
Can an amino acid boost brain radiation? new study seeks answers
Knowledge-focused Recruiting nowThis early-phase trial studies how to best give arginine (a natural amino acid) alongside whole brain radiation for people whose cancer has spread to the brain. Researchers will compare oral and IV arginine to find the dose that reaches the highest blood levels. The goal is to le…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: EARLY_PHASE1 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 17, 2026 03:09 UTC
-
Brain tumor surgery gets a High-Tech upgrade: microdialysis catheter collects Real-Time clues
Knowledge-focused Recruiting nowThis study is testing whether a small device called a microdialysis catheter can safely collect fluid samples from brain tumors during surgery. The goal is to measure biomarkers—natural substances that show how the tumor behaves. Researchers hope this information will lead to bet…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
-
Scientists use special PET scan to spy on immune cells in brain tumors
Knowledge-focused Recruiting nowThis early-stage trial tests a new imaging method that uses a radioactive tracer to find immune cells (CD8+ T-cells) inside brain tumors. The goal is to see if this PET scan can show where immune cells are active without needing a biopsy. About 20 adults with brain tumors schedul…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
-
Can heart drugs shield cancer patients from chemo damage?
Knowledge-focused Recruiting nowThis study watches people with HER2+ breast cancer that has spread, who are getting trastuzumab-based treatment. The main goal is to see how often heart problems happen, especially in those also taking beta blockers or other heart medications. A smaller part of the study tests if…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC
-
Brain cancer patients share telemedicine views in new study
Knowledge-focused Recruiting nowThis study asks 200 brain cancer patients about their experience with telemedicine compared to in-person visits. By collecting their feedback through surveys, researchers hope to learn how to improve care delivered remotely. The goal is to make telemedicine a better option for pe…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC