METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Clinical trials for METASTATIC MALIGNANT NEOPLASM IN THE BRAIN explained in plain language.
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New cocktail targets tough lung cancer in early trial
Disease control CompletedThis early-phase trial tested a new combination of drugs for people with extensive-stage small cell lung cancer that had not been treated before. The study added entinostat to standard treatments (atezolizumab, carboplatin, and etoposide) to see the best dose and possible side ef…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Immunotherapy duo shows promise against brain metastases in melanoma
Disease control CompletedThis study tested a combination of two immunotherapy drugs, low-dose ipilimumab and pembrolizumab, in 24 people with advanced melanoma that had spread to the brain. The goal was to see if the treatment could shrink or control brain tumors. Participants received the drugs intraven…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New combo therapy shows promise for brain metastases
Disease control CompletedThis early-stage study tested a combination of an immunotherapy drug (pembrolizumab) and precise radiation (stereotactic radiosurgery) in 25 people with melanoma or lung cancer that had spread to the brain. The main goal was to check for serious side effects. The approach aims to…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New hope for Hard-to-Treat breast cancer: drug combo shows promise
Disease control CompletedThis study tested whether adding the drug veliparib to standard chemotherapy (cisplatin) helps people with a fast-growing type of breast cancer called triple-negative or BRCA-related breast cancer, including those whose cancer has spread to the brain. About 344 adults took part. …
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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New MRI technique may solve brain scan mystery after radiation
Diagnosis CompletedThis study tested whether a special type of MRI (called DSC perfusion MRI) can help doctors tell the difference between radiation damage and tumor regrowth in people whose cancer has spread to the brain. Eight patients who had already received radiation therapy took part. The goa…
Matched conditions: METASTATIC MALIGNANT NEOPLASM IN THE BRAIN
Phase: NA • Sponsor: Emory University • Aim: Diagnosis
Last updated May 17, 2026 03:16 UTC