New combo therapy shows promise for brain metastases
NCT ID NCT02858869
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested combining the immunotherapy drug pembrolizumab with precise radiation (stereotactic radiosurgery) in 25 people with melanoma or lung cancer that had spread to the brain. The main goal was to check for serious side effects. Researchers also tracked how long participants lived and whether the treatment caused brain swelling. The approach aims to control the disease rather than cure it.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MELANOMA OF UNKNOWN PRIMARY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Emory University/Winship Cancer Institute
Atlanta, Georgia, 30322, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a One-Two punch of immune boosters revive cancer treatment?
- Could a personal coach at home boost energy for cancer patients?
- Personalized cancer care: genetic analysis may unlock targeted treatments for advanced lung cancer
- Can an immune checkpoint blocker outperform interferon in keeping mucosal melanoma at bay?
- Genetic roadmaps for advanced cancer: study tests whether expert navigation boosts targeted therapy use
- Morning vs. afternoon: could the clock boost immunotherapy against melanoma?