STAGE IV NON-SMALL CELL LUNG CANCER
Clinical trials for STAGE IV NON-SMALL CELL LUNG CANCER explained in plain language.
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Gene-Hacked immune cells take on tough cancers
Disease control Recruiting nowThis study tests a new treatment called IOV-4001 for people with advanced melanoma or non-small-cell lung cancer. The treatment uses a patient's own tumor-fighting immune cells, which are collected, genetically modified to remove a 'brake' called PD-1, and then infused back after…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1, PHASE2 • Sponsor: Iovance Biotherapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Supercharged immune cells take on Hard-to-Treat lung cancer
Disease control Recruiting nowThis early-stage trial is testing a new approach for people with advanced non-small cell lung cancer that has specific gene changes (EGFR, ALK, ROS1, or HER2). Doctors take immune cells from the patient's own tumor, boost them in the lab with a molecule called CD40L, and then giv…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Blood test may personalize lung cancer therapy
Disease control Recruiting nowThis study tests whether a simple blood test (ctDNA) can help doctors decide if adding chemotherapy to the immunotherapy drug cemiplimab works better for advanced lung cancer. About 63 people with stage IV or stage IIIB/C non-small cell lung cancer that hasn't been treated before…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: Fundación GECP • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New program aims to ease distress for advanced lung cancer patients
Symptom relief Recruiting nowThis study is testing a new program called POISE for people with stage IV non-small cell lung cancer who are on targeted therapy. The program includes four visits with a specially trained palliative care clinician to help patients cope with uncertainty and manage their cancer. Re…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New imaging agent may help doctors see which lung tumors are still growing during immunotherapy
Knowledge-focused Recruiting nowThis early-phase trial will test a new PET imaging agent called 64Cu-DOTA-pembrolizumab in 6 people with stage IV non-small cell lung cancer who are already on the immunotherapy drug pembrolizumab. The goal is to see if the imaging agent can safely tell the difference between tum…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Genetic roadmaps for advanced cancer: study tests whether expert navigation boosts targeted therapy use
Knowledge-focused Recruiting nowThis study tests whether having a specialist review genetic test results and guide treatment decisions can increase the use of targeted therapies for people with advanced solid tumors, including breast, lung, colorectal, and bladder cancers. Participants will have their tumor or …
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Ohio study aims to beat lung cancer with smarter testing
Knowledge-focused Recruiting nowThis large study in Ohio is looking at whether advanced genomic testing and immunotherapy decision support can help people with stage IV non-small cell lung cancer live longer and have a better quality of life. Researchers will compare standard care with a more personalized appro…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC