STAGE IV NON-SMALL CELL LUNG CANCER
Clinical trials for STAGE IV NON-SMALL CELL LUNG CANCER explained in plain language.
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Lung cancer hope: can targeted local therapy boost chemo for advanced disease?
Disease control OngoingThis study looks at whether adding local treatments like radiation or surgery to ongoing chemotherapy can help people with stage IV non-small cell lung cancer that has spread to a limited number of spots. About 218 participants are randomly assigned to get either maintenance chem…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Old drugs, new hope? ceritinib and docetaxel team up against tough lung cancer
Disease control OngoingThis early-phase study tests whether combining two cancer drugs—ceritinib and docetaxel—can safely help people with advanced non-small cell lung cancer that has not responded to other treatments. About 21 adults with stage IIIB or IV disease will receive the drugs to find the bes…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New drug combo shows promise in early cancer trial
Disease control OngoingThis early-phase trial tests a new drug called sEphB4-HSA combined with standard chemotherapy in people with advanced or metastatic solid tumors, including head and neck, pancreatic, lung, and gallbladder cancers. The goal is to find the best dose and see if the combination is sa…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New combo therapy aims to tame stage IV lung cancer
Disease control OngoingThis early-stage trial is for people with stage IV non-small cell lung cancer. It tests whether giving targeted radiation before or at the same time as two immunotherapy drugs (nivolumab and ipilimumab) is safe. The goal is to find the best radiation dose for different tumor loca…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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CRISPR Gene-Edited immune cells aim to fight lung cancer – but trial never started
Disease control TerminatedThis early-phase trial planned to test a new approach for people with metastatic non-small cell lung cancer. Doctors would remove immune cells from the tumor, edit them with CRISPR to remove a gene called CISH, and then infuse them back to help fight the cancer. However, the tria…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1, PHASE2 • Sponsor: Intima Bioscience, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Doctors inject chemo directly into lung tumors in early trial
Disease control OngoingThis early-phase trial tests a new method to deliver the chemotherapy drug cisplatin directly into lung tumors using a bronchoscope. The goal is to find the safest dose and see if this approach can help control stage IV lung cancer. Only 16 participants are enrolled, and the main…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: University of Vermont • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Blood test may predict cancer treatment success
Knowledge-focused OngoingThis study aims to create a tool that can predict whether a cancer patient will benefit from their prescribed therapy. Researchers are analyzing blood samples from 10,000 people with advanced lung cancer or melanoma before and during treatment. The goal is to develop an algorithm…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Sponsor: OncoHost Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC