Brain surgery probe could unlock tumor secrets

NCT ID NCT04047264

Recruiting now Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a small probe called a microdialysis catheter can be safely used during brain surgery to collect fluid samples from tumors. The goal is to measure biomarkers that could help doctors better understand and treat brain cancers like gliomas and metastatic tumors. About 100 adults undergoing brain surgery at Mayo Clinic will take part. The study focuses on safety and gathering information, not on providing a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors develop better ways to diagnose and monitor brain tumors during surgery.
What could go wrong: This is an early feasibility study with only 100 participants, so it may not lead to immediate changes in treatment. There is a small risk of bleeding or other complications from the microdialysis catheter.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain cancer glioblastoma glioma metastatic malignant neoplasm in the brain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA GLIOMA METASTATIC MALIGNANT NEOPLASM IN THE BRAIN

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Mayo Clinic in Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

Contact Email: •••••@•••••

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