METASTATIC LUNG NON-SMALL CELL CARCINOMA
Clinical trials for METASTATIC LUNG NON-SMALL CELL CARCINOMA explained in plain language.
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Custom-Made vaccine trial launches for Tough-to-Treat cancers
Disease control Recruiting nowThis early-stage study is testing the safety of a personalized vaccine designed to train a patient's immune system to attack their specific cancer. It is for adults with advanced breast cancer, melanoma, or non-small cell lung cancer that has continued to grow despite standard tr…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New pill targets 'Undruggable' cancer mutations in major trial
Disease control Recruiting nowThis study is testing a new oral drug, S241656, alone and in combination with other cancer therapies. It aims to find a safe and effective dose for adults with advanced cancers, including lung, pancreatic, and colorectal cancers, that have specific genetic mutations like KRAS or …
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Common painkiller tested as new weapon against lung cancer
Disease control Recruiting nowThis study is testing if adding diclofenac, a common anti-inflammatory painkiller, can help control advanced lung cancer that is starting to get worse while patients are on standard immunotherapy. The goal is to see if diclofenac can slow tumor growth and make the immunotherapy w…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New Two-Drug attack targets Tough-to-Treat lung cancer
Disease control Recruiting nowThis study is testing whether adding a new drug called GT103 to an existing immunotherapy (pembrolizumab) can better control advanced lung cancer that has a specific genetic change (STK11 mutation). The trial is for patients whose cancer has continued to grow despite prior treatm…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Smart radiation adjustments aim to protect Patients' hearts and lungs
Disease control Recruiting nowThis study is testing whether updating radiation treatment plans at set times during therapy can reduce damage to healthy heart and lung tissue in people with non-small cell lung cancer. Researchers want to see if this adaptive approach lowers side effects like lung inflammation …
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Brain cancer radiation showdown: one big dose vs. three smaller ones
Disease control Recruiting nowThis study aims to find the best radiation method for treating cancer that has spread to the brain. It compares giving one large radiation dose versus spreading the same total radiation over three smaller treatments. Researchers want to see which approach better controls the brai…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New drug duo aims to block growth of advanced lung cancer
Disease control Recruiting nowThis early-stage study is testing a new combination of two drugs, osimertinib and tegavivint, for people with a specific type of advanced lung cancer that has spread. The main goal is to find the safest and most effective dose of the drug pair. Researchers will also check if the …
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Targeted radiation aims to fight cancer in the spine while sparing memory
Disease control Recruiting nowThis study is testing a specialized radiation technique for patients with breast or lung cancer that has spread to the fluid around the brain and spine. The goal is to see if precisely targeting the entire brain and spinal cord with radiation, while avoiding a key memory area, ca…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New Two-Drug attack tested for Tough-to-Treat lung cancer
Disease control Recruiting nowThis study is testing if a new drug, SX-682, works better when given with an existing immunotherapy drug (pembrolizumab) for people with advanced non-small cell lung cancer that has spread or come back. The goal is to see if this combination can help the body's immune system figh…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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New hope for Tough-to-Treat lung cancer: scientists test powerful drug duo
Disease control Recruiting nowThis study is testing whether combining two targeted cancer drugs is safe and effective for people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. The trial is for patients whose cancer has continued to grow despite previous treatment…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Custom-Made vaccine aims to train immune system to fight advanced cancers
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to target the unique proteins on a patient's own cancer cells. It is being given alongside an existing immunotherapy drug (pembrolizumab) to see if the combination is safe and can help control advanced solid tumors that h…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New hope for tough lung cancers: early trial tests Dual-Attack therapy
Disease control Recruiting nowThis early-stage trial is testing a new combination of two immunotherapy drugs, PBF-1129 and nivolumab, for people with advanced non-small cell lung cancer that has returned or spread. The main goal is to find the safest dose and understand the side effects. Researchers also want…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1 • Sponsor: Dwight Owen • Aim: Disease control
Last updated Mar 18, 2026 14:42 UTC
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New proton beam trial aims to extend life for advanced cancer patients
Disease control Recruiting nowThis study is for people with breast or non-small cell lung cancer that has spread to the fluid-filled space around the brain and spinal cord. It compares two types of radiation therapy to see which one helps patients live longer. One method targets only the specific areas causin…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 16, 2026 15:27 UTC
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New drug duo tested in fight against tough lung cancers
Disease control Recruiting nowThis early-stage study is testing a new combination of two drugs, vismodegib and atezolizumab, for adults with advanced non-small cell lung cancer that has come back or spread. The main goal is to find the safest dose and understand the side effects of using these drugs together.…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE1 • Sponsor: Dwight Owen • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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New radiation approach targets cancer in brain and spine fluid
Disease control Recruiting nowThis study is testing a specialized radiation treatment for patients whose breast or lung cancer has spread to the fluid surrounding the brain and spinal cord. The treatment aims to target all areas where this type of cancer spread might occur. Researchers want to see if this app…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 09, 2026 14:22 UTC
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Researchers investigate sleepless nights in advanced lung cancer
Knowledge-focused Recruiting nowThis study aims to find out how common insomnia is in people whose lung cancer has spread to other parts of the body. Researchers will review medical records and ask 60 participants to complete a sleep questionnaire. The goal is to better understand this specific symptom burden i…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Doctors use scans to predict how lung cancer will respond to treatment
Knowledge-focused Recruiting nowThis study aims to learn how advanced lung cancer responds to a combination of chemotherapy, immunotherapy, and radiation by closely watching changes on PET/CT scans. It will enroll 80 patients with stage IV non-small cell lung cancer who are starting this standard treatment. The…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Phase: NA • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:55 UTC
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Mayo clinic tests 'Crystal Ball' for cancer treatment success
Knowledge-focused Recruiting nowThis study aims to collect tumor tissue samples from patients with various cancers to test a new diagnostic platform called Elephas. The goal is to see how accurately this tool can predict whether patients will respond to immunotherapy treatments before they begin. Researchers wi…
Matched conditions: METASTATIC LUNG NON-SMALL CELL CARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:26 UTC