Morning vs. afternoon: can timing boost cancer immunotherapy?
NCT ID NCT07405086
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether getting standard immunotherapy in the morning (before 11 am) or afternoon (after 12 pm) changes how well it fights advanced or metastatic solid tumors. Researchers think the body's internal clock (circadian rhythm) might affect immune activity. About 160 adults with several cancer types will be randomly assigned to morning or afternoon treatment, and the team will track how long the cancer stays under control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
immune checkpoint inhibitor
What this could lead to
If timing matters, this could help doctors schedule immunotherapy to improve its effectiveness against several types of advanced cancer.
What could go wrong
This is an early-phase study on timing, not a new drug. The effect may be small or absent, and results may not apply to all cancer types.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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OHSU Knight Cancer Institute
RECRUITINGPortland, Oregon, 97239, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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