New radiation approach targets cancer in the brain and spine

NCT ID NCT06910761

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase II trial tests whether a precise type of radiation called photon VMAT craniospinal irradiation can help people with breast or lung cancer that has spread to the fluid and lining around the brain and spinal cord. About 35 adults with this condition will receive radiation to the entire brain and spine. Researchers will measure how long the cancer stays under control in the central nervous system and how patients' quality of life changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

photon volumetric modulated arc radiotherapy (VMAT) craniospinal irradiation

What this could lead to

If successful, this could provide an effective radiation-based treatment option for cancer that has spread to the fluid and lining around the brain and spinal cord.

What could go wrong

This is a small, early-phase trial with only 35 participants, so results may not apply to everyone. Radiation to the brain and spine can cause side effects like fatigue, nausea, and neurological symptoms.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm lung cancer lung neoplasm Meningeal Carcinomatosis neoplastic meningitis non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Irvine Lennar

    RECRUITING

    Irvine, California, 92618, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact