STAGE IIIC LUNG CANCER AJCC V8
Clinical trials for STAGE IIIC LUNG CANCER AJCC V8 explained in plain language.
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New attack on stubborn lung cancer: zap tumors, then boost immunity
Disease control Recruiting nowThis study is for people with stage III non-small cell lung cancer that has started to grow again (progressed) after their initial chemo-radiation and immunotherapy. It tests whether using targeted treatments like surgery or radiation to attack specific progressing tumors, follow…
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Smart radiation adjustments aim to protect Patients' hearts and lungs
Disease control Recruiting nowThis study is testing whether updating radiation treatment plans at set times during therapy can reduce damage to healthy heart and lung tissue in people with non-small cell lung cancer. Researchers want to see if this adaptive approach lowers side effects like lung inflammation …
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Targeted pill trial aims to control advanced cancers by blocking key growth signals
Disease control Recruiting nowThis study is testing an oral medication called avapritinib for people with advanced solid tumors that have spread and have specific genetic changes (mutations in the CKIT or PDGFRA genes). The drug aims to block the signals that help these tumor cells grow, potentially controlli…
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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New Two-Drug attack tested for Tough-to-Treat lung cancer
Disease control Recruiting nowThis study is testing if a new drug, SX-682, works better when given with an existing immunotherapy drug (pembrolizumab) for people with advanced non-small cell lung cancer that has spread or come back. The goal is to see if this combination can help the body's immune system figh…
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Custom-Made vaccine aims to train immune system to fight advanced cancers
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to target the unique proteins on a patient's own cancer cells. It is being given alongside an existing immunotherapy drug (pembrolizumab) to see if the combination is safe and can help control advanced solid tumors that h…
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Double-Duty treatment trial aims to extend lives of vulnerable seniors with lung cancer
Disease control Recruiting nowThis study is for adults 70 and older with advanced non-small cell lung cancer. It compares two treatment approaches: immunotherapy alone versus immunotherapy combined with chemotherapy. The main goal is to see if the combination helps patients live longer and better control thei…
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Drug trial aims to stop lung cancer before it starts
Prevention Recruiting nowThis study is testing if a drug called canakinumab can prevent lung cancer in people who have suspicious, high-risk spots (nodules) in their lungs. About 50 participants will receive injections of the drug every 3 weeks for up to 8 cycles. The main goal is to see if the drug can …
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated Mar 30, 2026 14:34 UTC
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Yoga study aims to ease cancer treatment burden for patients and families
Symptom relief Recruiting nowThis study is testing whether a yoga program for patients and their caregivers can improve physical function and quality of life during radiation treatment for lung or esophageal cancer. It will compare yoga sessions to educational sessions to see which helps patients walk farthe…
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Tracking heart damage in lung cancer treatment: can personalized plans protect patients?
Knowledge-focused Recruiting nowThis study aims to understand how radiation and chemotherapy for advanced lung cancer affects heart health over time. Researchers will follow 100 patients receiving personalized treatment plans, measuring heart fitness and injury markers before, during, and for years after treatm…
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Could poop transplants ease cancer drug side effects?
Knowledge-focused Recruiting nowThis study aims to understand why some cancer patients develop severe diarrhea and colon inflammation (colitis) while taking powerful immunotherapy drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 patients with melanoma…
Matched conditions: STAGE IIIC LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 05, 2026 14:00 UTC