One-Two punch for lung cancer: can zapping tumors boost immune drugs?

NCT ID NCT03391869

First seen Nov 10, 2025 · Last updated Apr 19, 2026 · Updated 20 times

Summary

This study is for people with advanced non-small cell lung cancer that has spread. It tests if adding a local treatment like surgery or radiation to standard immunotherapy helps patients live longer. All participants first receive two immunotherapy drugs. If their cancer doesn't grow after 12 weeks, they are randomly assigned to either continue the drugs alone or to also receive targeted treatment to up to three tumor sites.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • MD Anderson League City

    League City, Texas, 77573, United States

  • MD Anderson West Houston

    Houston, Texas, 77079, United States

  • MD Anderson in Sugar Land

    Sugar Land, Texas, 77478, United States

  • MD Anderson in The Woodlands

    Conroe, Texas, 77384, United States

Conditions

Explore the condition pages connected to this study.