Vitamin a derivative joins immunotherapy in fight against advanced lung cancer

NCT ID NCT04919369

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 29 times

Summary

This early-stage trial tests a combination of all-trans retinoic acid (ATRA), a drug made from vitamin A, and atezolizumab, an immunotherapy, in 18 adults with advanced non-small cell lung cancer that has returned or spread. The main goal is to find the safest dose and understand side effects. Participants must have already tried standard treatments, and the study does not aim to cure the disease but to control it.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.