New drug combo aims to reboot immune system against lung cancer

NCT ID NCT05096663

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding an experimental drug (N-803) to the immunotherapy pembrolizumab can help control advanced non-small cell lung cancer better than standard treatments. The drug combo aims to activate natural killer cells and boost the immune system's attack on cancer. About 82 adults whose cancer worsened after prior immunotherapy are participating. The main goal is to see if the combo helps people live longer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2/3

Runs two stages together: whether the treatment works, then large-scale confirmation.

Participants

82 people

The number who actually took part.

Started

Mar 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants must have been assigned to S1800D by the Southwest Oncology Group (SWOG) Statistics and Data Management Center (SDMC). Assignment to S1800D is determined by the LUNGMAP or S1400 protocol * Participants must have measurable or non-measurable disease documented by computed tomography (CT) or magnetic resonance imaging (MRI). Measurable disease must be assessed within 28 days prior to randomization. Non-measurable disease must be assessed within 42 days prior to randomization. The CT from a combined positron emission tomography (PET)/CT may be used only if it is of diagnostic quality. All known sites of disease must be assessed and documented on the Baseline Tumor Assessment Form (RECIST 1.1) * Participants must have a CT or MRI scan of the brain to evaluate for central nervous system (CNS) disease within 42 days prior to sub-study randomization * Participants with spinal cord compression or brain metastases must have received local treatment to these metastases and remained clinically controlled and asymptomatic for at least 7 days following stereotactic radiation and/or 14 days following whole brain radiation, and prior to sub-study randomization * Participants with spinal cord compression or brain metastases must not have residual neurological dysfunction, unless no further recovery is expected, and the participant has been stable on weaning doses of corticosteroids (=\< 10 mg daily prednisone or equivalent) prior to sub-study randomization * Participants must have progressed (in the opinion of the treating investigator) following the most recent line of therapy for non-small cell lung cancer (NSCLC) * Participants with a known sensitizing mutation for which an FDA-approved targeted therapy for NSCLC exists (e.g. EGFR, ALK gene fusions, ROS1, BRAF, RET, NTRK, and MET sensitizing mutations), must have previously received at least one of the approved therapy(s) * Participants must have received exactly one line of anti-PD-1 or anti-PD-L1 therapy for advanced disease (stage IV or recurrent, or stage III in certain circumstances outlined below) given alone or in combination with platinum-based chemotherapy. Participants must have experienced disease progression during or after this regimen * Continuing the same agent(s) after progression counts as a single line of therapy. However, a change or addition in agent(s) after progression (e.g. the addition of chemotherapy to anti-PD-1 monotherapy after progression) counts as a subsequent line of therapy and would exclude the participant * For participants who received consolidation anti-PD-1 or anti-PD-L1 therapy following concurrent chemoradiation for Stage III disease as their only line of anti-PD-1 or anti-PD-L1 therapy: * If they experienced disease progression less than (\<) 365 days from the first date of anti-PD-1 or anti-PD-L1 therapy, this counts as the single line of anti-PD-1 or anti-PD-L1 therapy for advanced disease * If they experienced disease progression more than or equal to (\>=) 365 days from the first date of anti-PD-1 or anti-PD-L1 therapy, this is not considered a line of anti-PD-1 or anti-PD-L1 therapy for advanced disease * Participants must have recovered (=\< grade 1) from any side effects of prior therapy, except for alopecia * Participants must be able to safely receive at least one of the investigator's choice of standard of care regimens, per the current FDA-approved package insert * Note: Pemetrexed is not FDA-approved for squamous cell NSCLC and must not be used to treat participants with squamous cell NSCLC * Absolute neutrophil count (ANC) \>= 1.5 x 10\^3/uL (obtained within 28 days prior to sub-study randomization) * Platelet count \>= 100 x 10\^3/uL(obtained within 28 days prior to sub-study randomization) * Hemoglobin \>= 9 g/dL (obtained within 28 days prior to sub-study randomization) * Serum bilirubin =\< institutional upper limit of normal (IULN) (within 28 days prior to sub-study randomization). For participants with liver metastases, bilirubin must be =\< 5 x IULN * Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =\< 2 x IULN (within 28 days prior to sub-study randomization). For participants with liver metastases, ALT and AST must be =\< 5 x IULN * Serum creatinine =\< the IULN or calculated creatinine clearance \>= 50 mL/min using Cockcroft-Gault formula. This specimen must have been drawn and processed within 28 days prior to sub-study randomization * Participants' most recent Zubrod performance status must be 0-1 and be documented within 28 days prior to sub-study randomization * Participants must have history and physical exam must be obtained within 28 days prior to sub-study randomization * Participants with known human immunodeficiency virus (HIV) infection must be receiving anti-retroviral therapy and have an undetectable viral load at their most recent viral load test within 6 months prior to sub-study randomization * Participants must also be offered participation in banking and in the correlative studies for collection and future use of specimens * Note: As a part of the OPEN registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system * Participants must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines Exclusion Criteria: * Participants must not have leptomeningeal disease that requires CNS-specific treatment prior to registration and must not be planning to receive the CNS-specific treatment through the first cycle of the protocol therapy * Participants must not have experienced the following: * Any grade 3 or worse immune-related adverse event (irAE). Exception: asymptomatic nonbullous/nonexfoliative rash * Any unresolved grade 2 irAE * Any toxicity that led to permanent discontinuation of prior anti-PD-1/PD-L1 immunotherapy * Exception to the above: Toxicities of any grade that requires replacement therapy and has stabilized on therapy (e.g., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency) are allowed * Participants must not have any history of organ transplant that requires use of immunosuppressives * Participants must not have history of (non-infectious) pneumonitis that required steroids or current pneumonitis/interstitial lung disease * Participants must not have any known allergy or reaction to any component of the investigational formulations. If there is a known allergy or reaction to standard of care formulations, participants must be able to safely receive at least one of the standard of care options * Participants must not have any grade III/IV cardiac disease as defined by the New York Heart Association Criteria (i.e., participants with cardiac disease resulting in marked limitation of physical activity or resulting in inability to carry on any physical activity without discomfort), unstable angina pectoris, and myocardial infarction within 6 months prior to sub-study randomization, or serious uncontrolled cardiac arrhythmia * Participants must not have experienced any arterial thromboembolic events, including but not limited to myocardial infarction, transient ischemic attack, cerebrovascular accident, or unstable angina, within 6 months prior to sub-study randomization * Participants must not have an active or uncontrolled infection in the opinion of the treating investigator * Participants must not have a prior or concurrent malignancy whose natural history or treatment has the potential to interfere with the safety or efficacy assessment of the investigational regimen * Participants must not have any of following: * Cirrhosis at a level of Child-Pugh B (or worse) * Cirrhosis (any degree) and a history of hepatic encephalopathy * Or clinically meaningful ascites resulting from cirrhosis. Clinically meaningful ascites is defined as ascites from cirrhosis requiring diuretics or paracentesis * Participants must not have received anti-CTLA4 therapy (e.g. ipilimumab, tremelimumab), or other immune-modulatory therapy (e.g. anti-TIM-3, anti-LAG-3, anti-GITR, IL-2, IL-15) * Participants must not have received any prior systemic therapy (systemic chemotherapy, immunotherapy or investigational drug) within 21 days prior to sub-study randomization * Participants must not have received any radiation therapy within 14 days prior to sub-study randomization * Participants must not have received nitrosoureas or mitomycin-c within 42 days prior to sub-study randomization * Participants must not have received systemic treatment with corticosteroids (\> 10 mg daily prednisone or equivalent) or other immunosuppressive medications within 7 days prior to sub-study randomization. Inhaled or topical steroids, and adrenal replacement doses =\< 10 mg daily prednisone or equivalent are permitted in the absence of active autoimmune disease * Participants must not have received a live attenuated vaccination within 28 days prior to sub-study randomization. All COVID-19 vaccines that have received Food and Drug Administration (FDA) approval or FDA emergency use authorization are acceptable * Participants must not be planning to receive any concurrent chemotherapy, immunotherapy, biologic or hormonal therapy for cancer treatment while receiving treatment on this study * Participants must not have had a major surgery within 14 days prior to sub-study randomization. Participant must have fully recovered from the effects of prior surgery in the opinion of the treating investigator * Participants must not have an active autoimmune disease that has required systemic treatment within two years prior to sub-study randomization (i.e., with use of disease modifying agents, corticosteroids or immunosuppressive drugs). Replacement therapy (e.g., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency) is not considered a form of systemic treatment and is allowed * Participants must not have any history of primary immunodeficiency * Participants must not be pregnant or nursing. Women/men of reproductive potential must have agreed to use an effective contraceptive method during the study and 4 months after completion of study treatment. A woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months. In addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation. However, if at any point a previously celibate participant chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures during the study and 4 months after study completion

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abbott-Northwestern Hospital

    Minneapolis, Minnesota, 55407, United States

  • Academic Hematology Oncology Specialists

    Grosse Pointe Woods, Michigan, 48236, United States

  • Adams Cancer Center

    Gettysburg, Pennsylvania, 17325, United States

  • Addison Gilbert Hospital

    Gloucester, Massachusetts, 01930, United States

  • Adena Regional Medical Center

    Chillicothe, Ohio, 45601, United States

  • AdventHealth Hendersonville

    Hendersonville, North Carolina, 28792, United States

  • AdventHealth Infusion Center Asheville

    Asheville, North Carolina, 28803, United States

  • AdventHealth Infusion Center Haywood

    Clyde, North Carolina, 28721, United States

  • AdventHealth Infusion Center Weaverville

    Weaverville, North Carolina, 28787, United States

  • Alta Bates Summit Medical Center-Herrick Campus

    Berkeley, California, 94704, United States

  • AnMed Health Cancer Center

    Anderson, South Carolina, 29621, United States

  • Annie Penn Memorial Hospital

    Reidsville, North Carolina, 27320, United States

  • Arnold Palmer Cancer Center Medical Oncology Norwin

    N. Huntingdon, Pennsylvania, 15642, United States

  • Arnot Ogden Medical Center/Falck Cancer Center

    Elmira, New York, 14905, United States

  • Ascension Borgess Cancer Center

    Kalamazoo, Michigan, 49009, United States

  • Ascension Providence Hospitals - Novi

    Novi, Michigan, 48374, United States

  • Ascension Providence Hospitals - Southfield

    Southfield, Michigan, 48075, United States

  • Ascension Saint John Hospital

    Detroit, Michigan, 48236, United States

  • Ascension Saint Joseph Hospital

    Tawas City, Michigan, 48764, United States

  • Ascension Saint Mary's Hospital

    Saginaw, Michigan, 48601, United States

  • Ascension Via Christi Hospitals Wichita

    Wichita, Kansas, 67214, United States

  • Aurora Cancer Care-Grafton

    Grafton, Wisconsin, 53024, United States

  • Aurora Cancer Care-Milwaukee West

    Wauwatosa, Wisconsin, 53226, United States

  • Aurora Medical Center in Summit

    Summit, Wisconsin, 53066, United States

  • Aurora Saint Luke's Medical Center

    Milwaukee, Wisconsin, 53215, United States

  • Aurora Sinai Medical Center

    Milwaukee, Wisconsin, 53233, United States

  • Aurora West Allis Medical Center

    West Allis, Wisconsin, 53227, United States

  • Bayhealth Hospital Kent Campus

    Dover, Delaware, 19901, United States

  • Bayhealth Hospital Sussex Campus

    Milford, Delaware, 19963, United States

  • Beebe Health Campus

    Rehoboth Beach, Delaware, 19971, United States

  • Beebe South Coastal Health Campus

    Frankford, Delaware, 19945, United States

  • Beverly Hospital

    Beverly, Massachusetts, 01915, United States

  • Bhadresh Nayak MD PC-Sterling Heights

    Sterling Heights, Michigan, 48312, United States

  • Bozeman Deaconess Hospital

    Bozeman, Montana, 59715, United States

  • Bronson Battle Creek

    Battle Creek, Michigan, 49017, United States

  • Bronson Methodist Hospital

    Kalamazoo, Michigan, 49007, United States

  • CTCA at Western Regional Medical Center

    Goodyear, Arizona, 85338, United States

  • California Pacific Medical Center-Pacific Campus

    San Francisco, California, 94115, United States

  • Cancer Care Associates of York

    York, Pennsylvania, 17403, United States

  • Cancer Care Center of O'Fallon

    O'Fallon, Illinois, 62269, United States

  • Cancer Care Specialists of Illinois - Decatur

    Decatur, Illinois, 62526, United States

  • Cancer Center of Kansas - Wichita

    Wichita, Kansas, 67214, United States

  • Cancer Center of Kansas-Wichita Medical Arts Tower

    Wichita, Kansas, 67208, United States

  • Cancer Centers of Southwest Oklahoma Research

    Lawton, Oklahoma, 73505, United States

  • Cancer Institute at Saint Francis Hospital

    East Hills, New York, 11548, United States

  • Carle Cancer Center

    Urbana, Illinois, 61801, United States

  • Carle Physician Group-Effingham

    Effingham, Illinois, 62401, United States

  • Carle Physician Group-Mattoon/Charleston

    Mattoon, Illinois, 61938, United States

  • Carle on Vermilion

    Danville, Illinois, 61832, United States

  • Carlisle Regional Cancer Center

    Carlisle, Pennsylvania, 17015, United States

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Centralia Oncology Clinic

    Centralia, Illinois, 62801, United States

  • Cleveland Clinic Cancer Center Mansfield

    Mansfield, Ohio, 44906, United States

  • Cleveland Clinic Cancer Center Strongsville

    Strongsville, Ohio, 44136, United States

  • Cleveland Clinic Cancer Center/Fairview Hospital

    Cleveland, Ohio, 44111, United States

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Cleveland Clinic Mercy Hospital

    Canton, Ohio, 44708, United States

  • Cleveland Clinic Wooster Family Health and Surgery Center

    Wooster, Ohio, 44691, United States

  • Columbus Oncology and Hematology Associates Inc

    Columbus, Ohio, 43214, United States

  • Cone Health Cancer Center

    Greensboro, North Carolina, 27403, United States

  • Cone Health Cancer Center at Alamance Regional

    Burlington, North Carolina, 27215, United States

  • Cone Heath Cancer Center at Mebane

    Mebane, North Carolina, 27302, United States

  • Crossroads Cancer Center

    Effingham, Illinois, 62401, United States

  • Dartmouth Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Delaware Health Center-Grady Cancer Center

    Delaware, Ohio, 43015, United States

  • Divine Providence Hospital

    Williamsport, Pennsylvania, 17754, United States

  • Doctors Hospital

    Columbus, Ohio, 43228, United States

  • Duke Raleigh Hospital

    Raleigh, North Carolina, 27609, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Duke Women's Cancer Care Raleigh

    Raleigh, North Carolina, 27607, United States

  • Duluth Clinic Ashland

    Ashland, Wisconsin, 54806, United States

  • Durham VA Medical Center

    Durham, North Carolina, 27705, United States

  • Edward Hines Jr VA Hospital

    Hines, Illinois, 60141, United States

  • Edwards Comprehensive Cancer Center

    Huntington, West Virginia, 25701, United States

  • Eisenhower Medical Center

    Rancho Mirage, California, 92270, United States

  • Ephrata Cancer Center

    Ephrata, Pennsylvania, 17522, United States

  • Essentia Health - Deer River Clinic

    Deer River, Minnesota, 56636, United States

  • Essentia Health Cancer Center

    Duluth, Minnesota, 55805, United States

  • Essentia Health Hibbing Clinic

    Hibbing, Minnesota, 55746, United States

  • Essentia Health Sandstone

    Sandstone, Minnesota, 55072, United States

  • Essentia Health Virginia Clinic

    Virginia, Minnesota, 55792, United States

  • FirstHealth of the Carolinas-Moore Regional Hospital

    Pinehurst, North Carolina, 28374, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Froedtert Menomonee Falls Hospital

    Menomonee Falls, Wisconsin, 53051, United States

  • Froedtert West Bend Hospital/Kraemer Cancer Center

    West Bend, Wisconsin, 53095, United States

  • Genesee Cancer and Blood Disease Treatment Center

    Flint, Michigan, 48503, United States

  • Genesee Hematology Oncology PC

    Flint, Michigan, 48503, United States

  • Genesis Healthcare System Cancer Care Center

    Zanesville, Ohio, 43701, United States

  • Genesys Hurley Cancer Institute

    Flint, Michigan, 48503, United States

  • Good Samaritan Hospital Medical Center

    West Islip, New York, 11795, United States

  • Grant Medical Center

    Columbus, Ohio, 43215, United States

  • Great Lakes Cancer Management Specialists-Doctors Park

    East China Township, Michigan, 48054, United States

  • Great Lakes Cancer Management Specialists-Macomb Medical Campus

    Macomb, Michigan, 48044, United States

  • Great Lakes Cancer Management Specialists-Macomb Professional Building

    Warren, Michigan, 48093, United States

  • Great Lakes Cancer Management Specialists-Van Elslander Cancer Center

    Grosse Pointe Woods, Michigan, 48236, United States

  • Greater Regional Medical Center

    Creston, Iowa, 50801, United States

  • Gundersen Lutheran Medical Center

    La Crosse, Wisconsin, 54601, United States

  • Harold Alfond Center for Cancer Care

    Augusta, Maine, 04330, United States

  • HaysMed University of Kansas Health System

    Hays, Kansas, 67601, United States

  • Helen F Graham Cancer Center

    Newark, Delaware, 19713, United States

  • Hillcrest Hospital Cancer Center

    Mayfield Heights, Ohio, 44124, United States

  • Hurley Medical Center

    Flint, Michigan, 48503, United States

  • Huron Gastroenterology PC

    Ypsilanti, Michigan, 48106, United States

  • IRMC Cancer Center

    Indiana, Pennsylvania, 15701, United States

  • Illinois CancerCare - Washington

    Washington, Illinois, 61571, United States

  • Illinois CancerCare-Bloomington

    Bloomington, Illinois, 61704, United States

  • Illinois CancerCare-Canton

    Canton, Illinois, 61520, United States

  • Illinois CancerCare-Carthage

    Carthage, Illinois, 62321, United States

  • Illinois CancerCare-Dixon

    Dixon, Illinois, 61021, United States

  • Illinois CancerCare-Eureka

    Eureka, Illinois, 61530, United States

  • Illinois CancerCare-Galesburg

    Galesburg, Illinois, 61401, United States

  • Illinois CancerCare-Kewanee Clinic

    Kewanee, Illinois, 61443, United States

  • Illinois CancerCare-Macomb

    Macomb, Illinois, 61455, United States

  • Illinois CancerCare-Ottawa Clinic

    Ottawa, Illinois, 61350, United States

  • Illinois CancerCare-Pekin

    Pekin, Illinois, 61554, United States

  • Illinois CancerCare-Peoria

    Peoria, Illinois, 61615, United States

  • Illinois CancerCare-Peru

    Peru, Illinois, 61354, United States

  • Illinois CancerCare-Princeton

    Princeton, Illinois, 61356, United States

  • Indiana University/Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Kaiser Permanente - Harbor City

    Harbor City, California, 90710, United States

  • Kaiser Permanente - Kensington Medical Center

    Kensington, Maryland, 20895, United States

  • Kaiser Permanente - Largo Medical Center

    Largo, Maryland, 20774, United States

  • Kaiser Permanente - Panorama City

    Panorama City, California, 91402, United States

  • Kaiser Permanente Downtown Commons

    Sacramento, California, 95814, United States

  • Kaiser Permanente Los Angeles Medical Center

    Los Angeles, California, 90027, United States

  • Kaiser Permanente Medical Center - Santa Clara

    Santa Clara, California, 95051, United States

  • Kaiser Permanente Northwest

    Portland, Oregon, 97227, United States

  • Kaiser Permanente San Leandro

    San Leandro, California, 94577, United States

  • Kaiser Permanente Tysons Corner Medical Center

    McLean, Virginia, 22102, United States

  • Kaiser Permanente West Los Angeles

    Los Angeles, California, 90034, United States

  • Kaiser Permanente-Anaheim

    Anaheim, California, 92806, United States

  • Kaiser Permanente-Baldwin Park

    Baldwin Park, California, 91706, United States

  • Kaiser Permanente-Bellflower

    Bellflower, California, 90706, United States

  • Kaiser Permanente-Burke Medical Center

    Burke, Virginia, 22015, United States

  • Kaiser Permanente-Capitol Hill Medical Center

    Washington D.C., District of Columbia, 20002, United States

  • Kaiser Permanente-Fontana

    Fontana, California, 92335, United States

  • Kaiser Permanente-Gaithersburg Medical Center

    Gaithersburg, Maryland, 20879, United States

  • Kaiser Permanente-Irvine

    Irvine, California, 92618, United States

  • Kaiser Permanente-Oakland

    Oakland, California, 94611, United States

  • Kaiser Permanente-Ontario

    Ontario, California, 91761, United States

  • Kaiser Permanente-Riverside

    Riverside, California, 92505, United States

  • Kaiser Permanente-Roseville

    Roseville, California, 95661, United States

  • Kaiser Permanente-San Diego Zion

    San Diego, California, 92120, United States

  • Kaiser Permanente-San Francisco

    San Francisco, California, 94115, United States

  • Kaiser Permanente-San Marcos

    San Marcos, California, 92078, United States

  • Kaiser Permanente-Santa Teresa-San Jose

    San Jose, California, 95119, United States

  • Kaiser Permanente-South San Francisco

    South San Francisco, California, 94080, United States

  • Kaiser Permanente-Vallejo

    Vallejo, California, 94589, United States

  • Kaiser Permanente-Walnut Creek

    Walnut Creek, California, 94596, United States

  • Kaiser Permanente-Woodland Hills

    Woodland Hills, California, 91367, United States

  • Kaiser Permanente-Woodlawn Medical Center

    Baltimore, Maryland, 21244, United States

  • Knox Community Hospital

    Mount Vernon, Ohio, 43050, United States

  • Lafayette Family Cancer Center-EMMC

    Brewer, Maine, 04412, United States

  • Lahey Hospital and Medical Center

    Burlington, Massachusetts, 01805, United States

  • Lahey Medical Center-Peabody

    Peabody, Massachusetts, 01960, United States

  • Lawrence Memorial Hospital

    Lawrence, Kansas, 66044, United States

  • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

    Savannah, Georgia, 31405, United States

  • Licking Memorial Hospital

    Newark, Ohio, 43055, United States

  • Louisiana Hematology Oncology Associates LLC

    Baton Rouge, Louisiana, 70809, United States

  • MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford

    Biddeford, Maine, 04005, United States

  • MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford

    Sanford, Maine, 04073, United States

  • Marie Yeager Cancer Center

    Saint Joseph, Michigan, 49085, United States

  • Mary Greeley Medical Center

    Ames, Iowa, 50010, United States

  • Mary Imogene Bassett Hospital

    Cooperstown, New York, 13326, United States

  • McFarland Clinic PC - Ames

    Ames, Iowa, 50010, United States

  • McFarland Clinic PC-Boone

    Boone, Iowa, 50036, United States

  • McFarland Clinic PC-Jefferson

    Jefferson, Iowa, 50129, United States

  • McFarland Clinic PC-Marshalltown

    Marshalltown, Iowa, 50158, United States

  • McFarland Clinic PC-Trinity Cancer Center

    Fort Dodge, Iowa, 50501, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Medical Oncology Hematology Consultants PA

    Newark, Delaware, 19713, United States

  • Medical Oncology and Hematology Associates-West Des Moines

    Clive, Iowa, 50325, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Memorial Hospital of South Bend

    South Bend, Indiana, 46601, United States

  • Memorial Medical Center

    Modesto, California, 95355, United States

  • Memorial Medical Center

    Springfield, Illinois, 62781, United States

  • Memorial Medical Center - Las Cruces

    Las Cruces, New Mexico, 88011, United States

  • Mercy Cancer Center-West Lakes

    Clive, Iowa, 50325, United States

  • Mercy Hospital

    Cedar Rapids, Iowa, 52403, United States

  • Mercy Hospital Oklahoma City

    Oklahoma City, Oklahoma, 73120, United States

  • Mercy Medical Center-West Lakes

    West Des Moines, Iowa, 50266, United States

  • Mercyhealth Hospital and Cancer Center - Janesville

    Janesville, Wisconsin, 53548, United States

  • Mercyhealth Javon Bea Hospital - Rockton

    Rockford, Illinois, 61103, United States

  • Minneapolis VA Medical Center

    Minneapolis, Minnesota, 55417, United States

  • Mission Cancer and Blood - Laurel

    Des Moines, Iowa, 50314, United States

  • Missouri Baptist Medical Center

    St Louis, Missouri, 63131, United States

  • Missouri Baptist Outpatient Center-Sunset Hills

    Sunset Hills, Missouri, 63127, United States

  • Missouri Baptist Sullivan Hospital

    Sullivan, Missouri, 63080, United States

  • Mount Sinai Medical Center

    Miami Beach, Florida, 33140, United States

  • New Hampshire Oncology Hematology PA-Concord

    Concord, New Hampshire, 03301, United States

  • North Coast Cancer Care

    Sandusky, Ohio, 44870, United States

  • Northeast Georgia Medical Center-Gainesville

    Gainesville, Georgia, 30501, United States

  • Northside Hospital

    Atlanta, Georgia, 30342, United States

  • Northside Hospital - Duluth

    Duluth, Georgia, 30096, United States

  • Northside Hospital - Gwinnett

    Lawrenceville, Georgia, 30046, United States

  • Northwestern Medicine Lake Forest Hospital

    Lake Forest, Illinois, 60045, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • OhioHealth Marion General Hospital

    Marion, Ohio, 43302, United States

  • Olathe Health Cancer Center

    Olathe, Kansas, 66061, United States

  • Oncology Associates at Mercy Medical Center

    Cedar Rapids, Iowa, 52403, United States

  • Oncology Hematology Associates

    Greenville, Pennsylvania, 16125, United States

  • Oncology Hematology Associates of Saginaw Valley PC

    Saginaw, Michigan, 48604, United States

  • OptumCare Cancer Care at Charleston

    Las Vegas, Nevada, 89102, United States

  • OptumCare Cancer Care at Fort Apache

    Las Vegas, Nevada, 89148, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Owensboro Health Mitchell Memorial Cancer Center

    Owensboro, Kentucky, 42303, United States

  • PCR Oncology

    Arroyo Grande, California, 93420, United States

  • Palo Alto Medical Foundation Health Care

    Palo Alto, California, 94301, United States

  • Palo Alto Medical Foundation-Fremont

    Fremont, California, 94538, United States

  • Palo Alto Medical Foundation-Santa Cruz

    Santa Cruz, California, 95065, United States

  • Palo Alto Medical Foundation-Sunnyvale

    Sunnyvale, California, 94086, United States

  • Park Nicollet Clinic - Saint Louis Park

    Saint Louis Park, Minnesota, 55416, United States

  • Parkland Health Center - Farmington

    Farmington, Missouri, 63640, United States

  • Parkland Memorial Hospital

    Dallas, Texas, 75235, United States

  • Pottstown Hospital

    Pottstown, Pennsylvania, 19464, United States

  • Presbyterian Intercommunity Hospital

    Whittier, California, 90602, United States

  • Presbyterian Kaseman Hospital

    Albuquerque, New Mexico, 87110, United States

  • Presbyterian Rust Medical Center/Jorgensen Cancer Center

    Rio Rancho, New Mexico, 87124, United States

  • Prisma Health Cancer Institute - Butternut

    Greenville, South Carolina, 29605, United States

  • Prisma Health Cancer Institute - Easley

    Easley, South Carolina, 29640, United States

  • Prisma Health Cancer Institute - Eastside

    Greenville, South Carolina, 29615, United States

  • Prisma Health Cancer Institute - Faris

    Greenville, South Carolina, 29605, United States

  • Prisma Health Cancer Institute - Greer

    Greer, South Carolina, 29650, United States

  • Prisma Health Cancer Institute - Seneca

    Seneca, South Carolina, 29672, United States

  • Prisma Health Cancer Institute - Spartanburg

    Boiling Springs, South Carolina, 29316, United States

  • Prisma Health Greenville Memorial Hospital

    Greenville, South Carolina, 29605, United States

  • ProMedica Flower Hospital

    Sylvania, Ohio, 43560, United States

  • Ralph H Johnson VA Medical Center

    Charleston, South Carolina, 29401, United States

  • Randolph Hospital

    Asheboro, North Carolina, 27203, United States

  • Regions Hospital

    Saint Paul, Minnesota, 55101, United States

  • Renown Regional Medical Center

    Reno, Nevada, 89502, United States

  • Riverside Methodist Hospital

    Columbus, Ohio, 43214, United States

  • Saint Alphonsus Cancer Care Center-Boise

    Boise, Idaho, 83706, United States

  • Saint Ann's Hospital

    Westerville, Ohio, 43081, United States

  • Saint Francis Medical Center

    Cape Girardeau, Missouri, 63703, United States

  • Saint John Macomb-Oakland Hospital

    Warren, Michigan, 48093, United States

  • Saint Joseph Mercy Brighton

    Brighton, Michigan, 48114, United States

  • Saint Joseph Mercy Canton

    Canton, Michigan, 48188, United States

  • Saint Joseph Mercy Chelsea

    Chelsea, Michigan, 48118, United States

  • Saint Joseph Mercy Hospital

    Ann Arbor, Michigan, 48106, United States

  • Saint Luke's Cancer Institute - Boise

    Boise, Idaho, 83712, United States

  • Saint Luke's Cancer Institute - Fruitland

    Fruitland, Idaho, 83619, United States

  • Saint Luke's Cancer Institute - Meridian

    Meridian, Idaho, 83642, United States

  • Saint Luke's Cancer Institute - Nampa

    Nampa, Idaho, 83686, United States

  • Saint Luke's Cancer Institute - Twin Falls

    Twin Falls, Idaho, 83301, United States

  • Saint Vincent Hospital Cancer Center Green Bay

    Green Bay, Wisconsin, 54301, United States

  • Saint Vincent Hospital Cancer Center at Oconto Falls

    Oconto Falls, Wisconsin, 54154, United States

  • Saint Vincent Hospital Cancer Center at Saint Mary's

    Green Bay, Wisconsin, 54303, United States

  • Saint Vincent Hospital Cancer Center at Sturgeon Bay

    Sturgeon Bay, Wisconsin, 54235-1495, United States

  • Sainte Genevieve County Memorial Hospital

    Sainte Genevieve, Missouri, 63670, United States

  • Salina Regional Health Center

    Salina, Kansas, 67401, United States

  • Sanford Bismarck Medical Center

    Bismarck, North Dakota, 58501, United States

  • Sanford Broadway Medical Center

    Fargo, North Dakota, 58122, United States

  • Sanford Cancer Center Oncology Clinic

    Sioux Falls, South Dakota, 57104, United States

  • Sanford Joe Lueken Cancer Center

    Bemidji, Minnesota, 56601, United States

  • Sanford Roger Maris Cancer Center

    Fargo, North Dakota, 58122, United States

  • Sanford USD Medical Center - Sioux Falls

    Sioux Falls, South Dakota, 57117-5134, United States

  • Sechler Family Cancer Center

    Lebanon, Pennsylvania, 17042, United States

  • Siteman Cancer Center at Christian Hospital

    St Louis, Missouri, 63136, United States

  • Siteman Cancer Center at Saint Peters Hospital

    City of Saint Peters, Missouri, 63376, United States

  • Siteman Cancer Center at West County Hospital

    Creve Coeur, Missouri, 63141, United States

  • Siteman Cancer Center-South County

    St Louis, Missouri, 63129, United States

  • Solinsky Center for Cancer Care

    Manchester, New Hampshire, 03103, United States

  • South Pointe Hospital

    Warrensville Heights, Ohio, 44122, United States

  • Southern Illinois University School of Medicine

    Springfield, Illinois, 62702, United States

  • Southern Ohio Medical Center

    Portsmouth, Ohio, 45662, United States

  • Sparrow Hospital

    Lansing, Michigan, 48912, United States

  • Springfield Clinic

    Springfield, Illinois, 62702, United States

  • Springfield Regional Cancer Center

    Springfield, Ohio, 45504, United States

  • Springfield Regional Medical Center

    Springfield, Ohio, 45505, United States

  • Strecker Cancer Center-Belpre

    Belpre, Ohio, 45714, United States

  • Sutter Auburn Faith Hospital

    Auburn, California, 95602, United States

  • Sutter Medical Center Sacramento

    Sacramento, California, 95816, United States

  • Sutter Roseville Medical Center

    Roseville, California, 95661, United States

  • Sutter Solano Medical Center/Cancer Center

    Vallejo, California, 94589, United States

  • Temple University Hospital

    Philadelphia, Pennsylvania, 19140, United States

  • The Carle Foundation Hospital

    Urbana, Illinois, 61801, United States

  • The Don and Sybil Harrington Cancer Center

    Amarillo, Texas, 79106, United States

  • The Mark H Zangmeister Center

    Columbus, Ohio, 43219, United States

  • Torrance Memorial Physician Network - Cancer Care

    Torrance, California, 90505, United States

  • Tower Cancer Research Foundation

    Beverly Hills, California, 90211, United States

  • Trinity Health IHA Medical Group Hematology Oncology - Brighton

    Brighton, Michigan, 48114, United States

  • Trinity Health IHA Medical Group Hematology Oncology - Canton

    Canton, Michigan, 48188, United States

  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

    Chelsea, Michigan, 48118, United States

  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

    Ypsilanti, Michigan, 48197, United States

  • Trinity Health Saint Mary Mercy Livonia Hospital

    Livonia, Michigan, 48154, United States

  • Trinity's Tony Teramana Cancer Center

    Steubenville, Ohio, 43952, United States

  • Truman Medical Centers

    Kansas City, Missouri, 64108, United States

  • UMass Memorial Medical Center - University Campus

    Worcester, Massachusetts, 01655, United States

  • UPMC Altoona

    Altoona, Pennsylvania, 16601, United States

  • UPMC Camp Hill

    Camp Hill, Pennsylvania, 17011, United States

  • UPMC Cancer Center at UPMC Horizon

    Farrell, Pennsylvania, 16121, United States

  • UPMC Cancer Center at UPMC McKeesport

    McKeesport, Pennsylvania, 15132, United States

  • UPMC Cancer Center at UPMC Northwest

    Seneca, Pennsylvania, 16346, United States

  • UPMC Cancer Center-Natrona Heights

    Natrona Heights, Pennsylvania, 15065, United States

  • UPMC Cancer Center-Uniontown

    Uniontown, Pennsylvania, 15401, United States

  • UPMC Cancer Center-Washington

    Washington, Pennsylvania, 15301, United States

  • UPMC Cancer Centers - Arnold Palmer Pavilion

    Greensburg, Pennsylvania, 15601, United States

  • UPMC Hillman Cancer Center - Monroeville

    Monroeville, Pennsylvania, 15146, United States

  • UPMC Hillman Cancer Center - New Castle

    New Castle, Pennsylvania, 16105, United States

  • UPMC Hillman Cancer Center - Part of Frick Hospital

    Mount Pleasant, Pennsylvania, 15666, United States

  • UPMC Hillman Cancer Center - Passavant - Cranberry

    Cranberry Township, Pennsylvania, 16066, United States

  • UPMC Hillman Cancer Center Erie

    Erie, Pennsylvania, 16505, United States

  • UPMC Hillman Cancer Center at Butler Health System

    Butler, Pennsylvania, 16001, United States

  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion

    Mechanicsburg, Pennsylvania, 17050, United States

  • UPMC Memorial

    York, Pennsylvania, 17408, United States

  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus

    Harrisburg, Pennsylvania, 17109, United States

  • UPMC West Mifflin-Cancer Center Jefferson

    West Mifflin, Pennsylvania, 15122, United States

  • UPMC Western Maryland

    Cumberland, Maryland, 21502, United States

  • UPMC-Coraopolis/Heritage Valley Radiation Oncology

    Moon Township, Pennsylvania, 15108, United States

  • UPMC-Heritage Valley Health System Beaver

    Beaver, Pennsylvania, 15009, United States

  • UPMC-Johnstown/John P. Murtha Regional Cancer Center

    Johnstown, Pennsylvania, 15901, United States

  • UPMC-Mercy Hospital

    Pittsburgh, Pennsylvania, 15219, United States

  • UPMC-Passavant Hospital

    Pittsburgh, Pennsylvania, 15237, United States

  • UPMC-Saint Clair Hospital Cancer Center

    Pittsburgh, Pennsylvania, 15243, United States

  • UT Southwestern Clinical Center at Richardson/Plano

    Richardson, Texas, 75080, United States

  • UT Southwestern/Simmons Cancer Center-Dallas

    Dallas, Texas, 75390, United States

  • UT Southwestern/Simmons Cancer Center-Fort Worth

    Fort Worth, Texas, 76104, United States

  • Unity Hospital

    Fridley, Minnesota, 55432, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

  • University of Iowa Healthcare Cancer Services Quad Cities

    Bettendorf, Iowa, 52722, United States

  • University of Kansas Cancer Center - Lee's Summit

    Lee's Summit, Missouri, 64064, United States

  • University of Kansas Cancer Center - North

    Kansas City, Missouri, 64154, United States

  • University of Kansas Cancer Center at North Kansas City Hospital

    North Kansas City, Missouri, 64116, United States

  • University of Kansas Cancer Center-Overland Park

    Overland Park, Kansas, 66210, United States

  • University of Kansas Health System Saint Francis Campus

    Topeka, Kansas, 66606, United States

  • University of Kansas Hospital-Indian Creek Campus

    Overland Park, Kansas, 66211, United States

  • University of Kansas Hospital-Westwood Cancer Center

    Westwood, Kansas, 66205, United States

  • University of Kentucky/Markey Cancer Center

    Lexington, Kentucky, 40536, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • University of New Mexico Cancer Center

    Albuquerque, New Mexico, 87102, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Pittsburgh Cancer Institute (UPCI)

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Rochester

    Rochester, New York, 14642, United States

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

  • Veterans Administration Medical Center - Birmingham

    Birmingham, Alabama, 35233, United States

  • Veterans Affairs Connecticut Healthcare System-West Haven Campus

    West Haven, Connecticut, 06516, United States

  • Veterans Affairs Medical Center - San Francisco

    San Francisco, California, 94121, United States

  • Virtua Samson Cancer Center

    Moorestown, New Jersey, 08057, United States

  • Virtua Voorhees

    Voorhees Township, New Jersey, 08043, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

  • WellSpan Health-York Cancer Center

    York, Pennsylvania, 17403, United States

  • WellSpan Health-York Hospital

    York, Pennsylvania, 17403, United States

  • WellSpan Medical Oncology and Hematology

    Chambersburg, Pennsylvania, 17201, United States

  • West Michigan Cancer Center

    Kalamazoo, Michigan, 49007, United States

  • West Virginia University Charleston Division

    Charleston, West Virginia, 25304, United States

  • West Virginia University Healthcare

    Morgantown, West Virginia, 26506, United States

  • William E Kahlert Regional Cancer Center/Sinai Hospital

    Westminster, Maryland, 21157, United States

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