Can adding surgery or radiation to a targeted pill slow lung cancer better?

NCT ID NCT03410043

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding surgery or radiation to the targeted drug osimertinib helps people with advanced EGFR-mutant non-small cell lung cancer live longer without their cancer growing. About 173 participants will receive either osimertinib alone or osimertinib plus local treatments. The goal is to see if the combination improves cancer control.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • UCSF Medical Center-Mount Zion

    San Francisco, California, 94115, United States

  • University of Colorado

    Denver, Colorado, 80217-3364, United States

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Other studies related to the condition(s) this trial covers.