New drug duo targets hard-to-treat lung cancer
NCT ID NCT04250545
First seen Dec 10, 2025 · Last updated May 15, 2026 · Updated 19 times
Summary
This early-phase trial tests two experimental drugs, sapanisertib and telaglenastat, in people with advanced non-small cell lung cancer that has spread to the brain or other areas. The main goals are to find the safest dose and see if the combination can shrink tumors or slow the disease. About 22 participants will take part.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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City of Hope at Irvine Lennar
Irvine, California, 92618, United States
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Keck Medicine of USC Koreatown
Los Angeles, California, 90020, United States
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
Conditions
Explore the condition pages connected to this study.