New combo therapy targets tough lung cancer in early trial
NCT ID NCT05166616
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests the safety and best dose of a new drug, minnelide, when given with the standard drug osimertinib for people with advanced EGFR-mutated non-small cell lung cancer. The trial enrolls about 8 adults whose cancer has spread or cannot be removed by surgery. The goal is to see if the combination can work better than osimertinib alone, while monitoring side effects closely.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
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Other studies related to the condition(s) this trial covers.
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