New combo targets hard-to-treat lung cancer in early trial

NCT ID NCT05166616

First seen Mar 05, 2026 · Last updated Jun 14, 2026 · Updated 19 times

Summary

This early-phase trial tests the safety and best dose of a new drug called minnelide when combined with the standard drug osimertinib for people with advanced EGFR-mutant non-small cell lung cancer. Only 8 participants are enrolled. The goal is to find side effects and the right dose, not to cure the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.