PSYCHOLOGICAL DISTRESS
Clinical trials for PSYCHOLOGICAL DISTRESS explained in plain language.
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New diabetes program helps hill tribe elders control blood sugar
Disease control CompletedThis study tested a 6-week diabetes self-management program for ethnic minority elderly (aged 60+) in rural Thailand. The program included weekly group sessions on diet, exercise, medication, and emotional coping, plus two home visits. Researchers measured changes in blood sugar …
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Taipei Medical University • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New program aims to help young men stay out of prison after release
Disease control CompletedThis completed study tested a program called RISE (Resiliency in Stressful Experiences) for young men ages 18-35 leaving state prisons in Florida. The program combines trauma counseling with practical help like housing and job support. Researchers measured whether participants ha…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Florida State University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Can a 24-Week program reduce diabetes and distress in job seekers?
Disease control CompletedThis study tested a 24-week lifestyle program for unemployed adults receiving employment services. The program included online classes and one-on-one coaching on topics like healthy eating, stress management, and exercise. Researchers measured changes in weight, blood pressure, a…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Massive french study tests app to curb suicide rates
Prevention CompletedThis study tested whether promoting a free web and mobile tool called StopBlues could reduce suicides and suicide attempts in the general population. Over 100,000 adults in 42 French communities took part, with some communities actively promoting the tool and others not. The goal…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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Can a 5-Session program lift mood? large study tests community mental health help
Symptom relief CompletedThis study tested a brief, community-based psychological program called Problem Management Plus to see if it can reduce depression, anxiety, and distress. Over 1,200 adults with mild to moderate symptoms took part. The program focuses on practical problem-solving skills in just f…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: George Washington University • Aim: Symptom relief
Last updated Jun 27, 2026 12:39 UTC
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Talking therapy shows promise for vaginismus distress
Symptom relief CompletedThis study tested whether a structured cognitive behavioral therapy (CBT) program could reduce psychological distress and improve problem-solving skills in women with vaginismus. Sixty women were randomly assigned to either CBT sessions over three months or routine care. The resu…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Delta University for Science and Technology • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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New therapy blends faith and science to heal teen trauma
Symptom relief CompletedThis study tested a 6-session group program for teenagers struggling with emotional distress after the 2019 Christchurch mosque attacks. The program combined proven therapy techniques with Islamic principles. 26 teens took part, and researchers measured changes in emotional sympt…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University of Otago • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Short therapy shows promise for refugee mental health
Symptom relief CompletedThis pilot study tested a short psychological program called Problem Management Plus (PM+) in 64 refugees and asylum seekers in Switzerland. The program, developed by the World Health Organization, uses simple techniques like problem-solving and stress management to reduce psycho…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University of Zurich • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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New care approach eases emotional toll of menopausal bladder issues
Symptom relief CompletedThis study tested a continuous care model in 98 postmenopausal women with urinary incontinence. The goal was to see if ongoing support and education could reduce psychological distress and improve quality of life. Participants were randomly assigned to receive the continuous care…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Al-Quds University • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Ear-Zap device calms stressed students in new trial
Symptom relief CompletedThis study tested a non-invasive device that sends mild electrical pulses to a nerve in the ear (taVNS) to see if it lowers stress and distress in university students. Forty students with high distress levels received either real or fake stimulation for five days. The researchers…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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New nursing method eases caregiver burnout in brain injury cases
Symptom relief CompletedThis study tested a special nursing approach, called the Tidal Model, to help caregivers of people with traumatic brain injury. 18 caregivers took part and the program aimed to reduce their anxiety, depression, and burnout. The approach focused on understanding each caregiver's p…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Art therapy eases death anxiety for ICU nurses in new study
Symptom relief CompletedThis study tested whether expressive arts therapy—like drawing, painting, or writing—can help intensive care unit (ICU) nurses feel less anxious about death. 66 nurses took part, with half attending weekly art therapy sessions for six weeks. The goal was to see if this creative a…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Cash and companionship: a new way to ease mental distress?
Symptom relief CompletedThis study tested whether small cash grants and peer mentoring could help transgender people who are struggling financially feel less psychological distress. 360 transgender adults experiencing material hardship were split into three groups: one got a single grant, another got mo…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Music eases anxiety during prostate cancer therapy, study finds
Symptom relief CompletedThis study tested whether listening to music during radionuclide treatment helps prostate cancer patients feel less anxious and distressed. Sixty men were split into two groups: one listened to their choice of instrumental music through headphones during treatment, while the othe…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Dokuz Eylul University • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Online training aims to ease paramedic burnout and PTSD
Symptom relief CompletedThis study tested two online courses designed to help paramedics in Singapore manage stress, anxiety, depression, and burnout during the COVID-19 pandemic. 63 paramedics took part, completing six weekly online modules. The goal was to see which course better improved mental healt…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Singapore General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Mindfulness during pregnancy may ease stress and depression
Symptom relief CompletedThis study tested whether an 8-week mindfulness-based cognitive therapy (MBCT) program can reduce stress, anxiety, and depression in pregnant women at risk for psychological distress. 84 women participated, with some receiving MBCT and others getting usual care. The goal was to u…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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New phone programs ease cancer survivors' symptoms and distress
Symptom relief CompletedThis study tested two phone-based programs for cancer survivors and their caregivers to help manage physical and emotional symptoms after treatment ends. 555 survivors and their caregivers took part. The programs provided information and counseling to reduce distress and improve …
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University of Arizona • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Talking therapy shows promise for easing infertility distress
Symptom relief CompletedThis study tested whether a type of talk therapy called Acceptance and Commitment Therapy (ACT) can help people struggling with the emotional stress of infertility. Nine adults with infertility took part in 12 therapy sessions. Researchers measured changes in mood, stress, and ho…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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App + coach: a new way to tackle everyday stress?
Symptom relief CompletedThis pilot study tested a 4-month app-based mental health program with coaching for 25 adults in Austria and Italy who felt stressed. Participants used the app for exercises, diaries, and bi-weekly video chats with a coach. The goal was to see if the program was easy to use and i…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Medical University Innsbruck • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Massage once a month for a year: a stress fix for healthcare heroes?
Symptom relief CompletedThis pilot study tested whether getting a 30-minute Swedish massage once a month for a year could improve the mental and physical health of healthcare workers in a hospital. Twenty-five staff who work at least half-time with patient care took part. Researchers measured stress, an…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University Hospital, Linkoeping • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Dance-Walk study shows promise for mental well-being
Symptom relief CompletedThis study tested a 4-week movement program called Dance-Walk in 117 adults seeking mental health support. Participants either started the program right away or waited. The goal was to see if combining dance and walking could improve body awareness, energy, and reduce stress, anx…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Vilnius University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Heart patients find relief with online therapy program
Symptom relief CompletedThis study tested a 9-week internet-based cognitive behavioral therapy (CBT) program designed to reduce stress, anxiety, and depression in people with stable heart disease. 215 adults with heart disease and elevated stress or mood symptoms took part. The program was personalized …
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University Hospital, Linkoeping • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Hand acupressure may ease nurse burnout, small study finds
Symptom relief CompletedThis study tested whether self-acupressure on two hand points (Shenmen and Neiguan) could reduce stress, anxiety, depression, and burnout in 160 nurses. Nurses in the acupressure group pressed these points for about 2 minutes twice daily for two weeks. The study measured their sy…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Kaohsiung Veterans General Hospital. • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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New app aims to ease trauma after intensive care
Symptom relief CompletedThis study tested whether a mobile app called Messy Memories could help people who had been in the intensive care unit (ICU) deal with distressing memories. The app guides users to record and process a difficult memory on their own. Researchers wanted to see if people would actua…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Can breathing to music ease caregiver stress?
Symptom relief CompletedThis pilot study tested whether music breathing therapy delivered via Zoom can help reduce stress and improve quality of life for parents caring for a child newly diagnosed with cancer. Sixty caregivers participated in weekly one-hour sessions for two months. The goal was to see …
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Jun 26, 2026 16:45 UTC
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Meditation app shows promise for depression in 1,157-Person study
Symptom relief CompletedThis study tested a free smartphone app called the Healthy Minds Program (HMP) in over 1,100 US adults with mild to moderate depression. Participants used the app for 4 weeks and were compared to those who received only educational content or were placed on a waitlist. The goal w…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Jun 26, 2026 15:22 UTC
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Fish oil pills could boost mood and memory, small study finds
Symptom relief CompletedThis study tested whether daily omega-3 supplements (fish oil) can help reduce stress, anxiety, depression, and improve memory and sleep in 64 Saudi adults who reported high stress. Participants took either omega-3 or a placebo for three months. Those taking omega-3 reported lowe…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Umm Al-Qura University • Aim: Symptom relief
Last updated Jun 26, 2026 14:05 UTC
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Tailored talk therapy shows promise for earthquake trauma
Symptom relief CompletedThis pilot study tested a culturally adapted form of cognitive behavioral therapy (CA-CBT) for adults who experienced the earthquakes in Türkiye and have high psychological distress. Sixty participants received 8 group sessions focusing on trauma education, emotion regulation, an…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Koç University • Aim: Symptom relief
Last updated Jun 26, 2026 12:43 UTC
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Could a simple community program reduce partner violence? new study tests it
Knowledge-focused CompletedThis study tested a combined program (WINGS+PM+) for women experiencing intimate partner violence (IPV) and mental distress in Kenyan informal settlements. 260 women were randomly assigned to either the combined program or a shorter psychological support alone. The goal was to se…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Can smartphones replace In-Person therapy during a pandemic?
Knowledge-focused CompletedThis study looked at whether digital services like smartphone apps can help people with psychosomatic disorders continue their treatment during the COVID-19 pandemic, when social distancing and hygiene rules limit in-person therapy. About 2000 patients from clinics took part, usi…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Jacobs University Bremen gGmbH • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New program aims to help Long-COVID patients with online screening and personal support
Knowledge-focused CompletedThis study tested a program for people with long-COVID that includes an online screening, a detailed in-person assessment, and digital training modules with a personal counselor. 192 participants from Bavaria took part to see if this approach is practical and helpful. The goal wa…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Prof. Dr. Sonia Lippke • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Study reveals mental health ties to diabetes Self-Care in teens and young adults
Knowledge-focused CompletedThis completed study looked at 115 young people aged 10 to 25 with type 1 diabetes in Spain. Participants filled out an online survey about their mental health, eating habits, and how well they manage their diabetes. The goal was to see if these factors differ by age and sex, and…
Matched conditions: PSYCHOLOGICAL DISTRESS
Sponsor: University of Alicante • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Navy tests phone app to keep sailors mentally fit
Knowledge-focused CompletedThis study tested a smartphone app called Cogito Companion to see if it could help assess psychological distress in Navy sailors returning to the U.S. 279 sailors participated, with some using the app and others using standard self-help resources. The main goal was to measure how…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: VA Eastern Colorado Health Care System • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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PCOS symptom check: new tool could improve patient care
Knowledge-focused CompletedThis study created and tested a new questionnaire to measure both the severity of Polycystic Ovary Syndrome (PCOS) symptoms and the distress they cause. Researchers enrolled 227 women diagnosed with PCOS in Turkey. Participants completed online surveys, including the new inventor…
Matched conditions: PSYCHOLOGICAL DISTRESS
Sponsor: Abant Izzet Baysal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Mind over microbes? new study probes Brain-Immune link in 700 slovaks
Knowledge-focused CompletedThis completed study in Slovakia examined how psychological factors like resilience, stress, and positive thinking relate to the body's immune system. Researchers measured immune markers in blood and compared them to mental health questionnaires in 700 adults, including people in…
Matched conditions: PSYCHOLOGICAL DISTRESS
Sponsor: Comenius University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New study aims to uncover hidden anxiety in teens
Knowledge-focused CompletedThis study looked at 80 teenagers aged 14 to 17 who were already experiencing emotional or relationship distress. Researchers used a questionnaire to measure anxiety and other psychological struggles. For those with high distress, the study also tested a short program of 10 couns…
Matched conditions: PSYCHOLOGICAL DISTRESS
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Plasma donation study: frequent Donors' health under the microscope
Knowledge-focused CompletedThis study looked at whether donating plasma more often affects protein levels, inflammation, and mental health in male blood donors. 120 men were split into three groups: one donated plasma three times every two weeks, another every two weeks, and a third donated whole blood eve…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: Sykehuset Innlandet HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Neck pain study reveals hidden role of personality and stigma
Knowledge-focused CompletedThis study looked at whether people with long-term neck pain (cervical myofascial pain syndrome) are more likely to have a 'Type D' or distressed personality and feel stigma about their condition. Researchers compared 54 patients with healthy individuals using questionnaires. The…
Matched conditions: PSYCHOLOGICAL DISTRESS
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Childhood trauma linked to worse jaw function in new study
Knowledge-focused CompletedThis study looked at how traumatic experiences—both in childhood and later in life—impact jaw function and quality of life in people with temporomandibular joint disorder (TMD). Researchers compared 102 adults with TMD to healthy volunteers using questionnaires about trauma, jaw …
Matched conditions: PSYCHOLOGICAL DISTRESS
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Cardiac arrest survivors' brain function tracked for two years
Knowledge-focused CompletedThis study looks at how cardiac arrest affects thinking, memory, emotions, and sleep over time. About 200 survivors will take detailed brain tests 7 and 24 months after their cardiac arrest. Their results will be compared to heart attack patients who did not have a cardiac arrest…
Matched conditions: PSYCHOLOGICAL DISTRESS
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Chilean study checks if psychological distress survey works in spanish
Knowledge-focused CompletedThis study tested a Spanish version of the Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM), a questionnaire that measures psychological distress, in over 1,100 people in Chile. Participants included mental health patients, university students, and community memb…
Matched conditions: PSYCHOLOGICAL DISTRESS
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Free cash for 12 months: does it really help?
Knowledge-focused CompletedThis study tested whether giving low-income Los Angeles residents $1,000 every month for a year helps reduce financial stress and improve well-being. Over 8,000 adults with children and low incomes took part. Researchers tracked changes in mental health, housing, food security, a…
Matched conditions: PSYCHOLOGICAL DISTRESS
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC