PSYCHOLOGICAL DISTRESS

This study tests a mobile health app called mSYNC designed to help prevent HIV in people who use drugs and visit the emergency department. The app provides counseling and support for risk behaviors, mental health, and access to care. Researchers want to see if the app is acceptab…

This study tests whether a leadership training program can help National Guard leaders better support their team's mental health. About 5,400 Guard members, leaders, and their spouses will take part. The training includes a one-hour online course, a behavior tracking exercise, an…

This study is testing a family-centered program called SHINE, designed to support teenagers aged 10 to 17 who have a parent diagnosed with cancer. The program includes about four sessions over eight weeks, focusing on cancer education, family communication, coping skills, and emo…

This trial tests whether a guided digital program delivered through a mobile app can reduce anxiety and depression in young adults (ages 18–40) who have fertility-related distress after a cancer diagnosis. Participants use the app to complete four modules covering coping skills, …

This pilot study tests a financial psycho-oncology program for cancer patients facing financial hardship. Participants attend six one-hour sessions over three months that combine emotional support with practical financial education. The study aims to see if the program is feasibl…

This study tests whether adding peer support helps veterans use mental health apps more effectively to reduce psychological distress like depression, anxiety, and PTSD. About 384 veterans from three VA primary care clinics will try different levels of peer coaching while using th…

This study tests whether an interactive, nature-based virtual reality (VR) program can reduce anxiety and depression in older adults staying in the hospital with chronic health conditions. One hundred hospitalized adults aged 60 and older will be randomly assigned to either an in…

This trial tests a smartphone app called E-breathing that detects when a teen is feeling distressed and prompts them to practice slow-paced breathing. The study includes 100 adolescents aged 11 to 17 in Hong Kong who have at least mild symptoms of depression, anxiety, or stress. …

This study tests whether a 20-minute mandala coloring session can reduce childbirth fear and anxiety in fathers whose partners are giving birth for the first time. Fathers waiting outside the delivery room are randomly assigned to either color a mandala or receive standard care. …

This study tests a 13-week remote stress recovery program for people who had a heart attack before age 55 and still feel distressed. The program includes online sessions with a therapist, a workbook, and videos. The goal is to see if a larger trial is possible by checking how man…

This study tests a special type of acupuncture—dense cranial electroacupuncture plus body acupuncture—in 148 teens aged 15-22 with mild to moderate anxiety or depression. Participants receive treatment twice a week for 8 weeks, and researchers measure changes in anxiety, depressi…

This study tests whether a web-based program called YOLO, based on Acceptance and Commitment Therapy (ACT), can help university students manage psychological distress, anxiety, and academic stress. Around 1,000 students from the University of Bologna will either get immediate acc…

This study tests whether an online mental health platform called ENYOY can reduce psychological distress in young people aged 16 to 25 who are on waiting lists for mental health care. Participants are randomly assigned to either get access to the platform plus usual care, or usua…

This study tests an 8-week digital program that helps migrants in Sweden improve their mental health through better sleep, diet, physical activity, and social connections. 240 adults with moderate stress, anxiety, or depression will either get the program or a general wellness mo…

This study tests whether an interactive virtual reality (VR) program can help reduce pain, anxiety, and fatigue in 20 hospitalized palliative care patients. Participants use a VR headset with sensors to interact with a calming natural environment for 10 minutes daily over 14 days…

Many cancer survivors live with a persistent fear that their cancer will return, which can harm their mental health and daily life. This pilot study will test a type of talking therapy called metacognitive therapy (MCT) against relaxation therapy in 120 survivors. The goal is to …

This study tests whether a teleconsultation with a specially trained nurse can reduce psychological distress in adults recently diagnosed with a primary brain tumor. 58 participants will be randomly assigned to receive either usual care or usual care plus one nurse-led video call…

This study looks at how people feel emotionally when they go through cancer genetic testing, and whether talking to a psychologist helps. It follows 220 adults who are having their first genetic counseling session. Some choose to use the psychological support offered, while other…

This study tests whether a World Health Organization program called Self-Help Plus (SH+) can help reduce stress in social service workers. About 50 workers from four institutions in Istanbul will be randomly assigned to either receive SH+ plus usual support, or usual support alon…

This study looks at whether a short gratitude writing exercise can improve optimism and gratitude and reduce psychological distress in female university students. About 96 students with mild to moderate distress will be split into three groups: one writes about things they are gr…

This study looks at whether giving both food assistance and psychological counseling helps young adults aged 18-25 who face food insecurity and mental health issues. Participants will receive weekly food aid for a year, and half will also get twice-monthly therapy for six months.…