POST OPERATIVE PAIN

This study tested whether a multi-port epidural catheter provides better pain relief than a single-port catheter after chest or upper belly surgery. 240 adults aged 18 to 75 took part. The main goal was to see which type reduced the need for extra pain medicine or replacement of …

This study tested a single injection of F14, a slow-release painkiller, in 151 adults having knee replacement surgery. The goal was to see if it reduces pain and the need for opioid painkillers after surgery. Results suggest it may improve pain control and knee movement during re…

This study tested two different numbing injections for pain after collarbone surgery in 50 adults. One block targets the shoulder area, the other targets the chest wall. The goal was to see which provides longer pain relief and reduces the risk of temporary diaphragm paralysis, a…

This study tested a new medicine called MR-107A-02 to see if it can safely relieve pain after bunionectomy (foot surgery). About 410 adults took part. The goal was to measure pain relief and how much extra opioid painkiller was needed. The study compared the new drug to a placebo…

This study tested two pain-relief methods after modified radical mastectomy: an ultrasound-guided nerve block (erector spinae plane block) and local wound infiltration (drain block). 37 women participated, and researchers measured how much morphine they needed in the first day af…

This study looked at whether a quadratus lumborum (QL) nerve block can help manage pain after robotic surgery for pelvic organ prolapse. 70 women were randomly assigned to receive either the standard enhanced recovery protocol or the QL block. The goal was to see if the block low…

This study tested a new drug called CPL-01 to see how well it controls pain after open inguinal hernia repair. 518 adults received either CPL-01, a placebo, or an active painkiller. The main goal was to measure pain levels during activity using a 0-10 scale.

This study compared two methods of pain relief after radical cystectomy (bladder removal) surgery: thoracic epidural analgesia and ultrasound-guided erector spinae plane block. Twenty patients aged 40-70 participated. The goal was to see which method provides better pain control …

This study tested a new approach for knee replacement surgery in 70 people with severe knee arthritis. In addition to the standard knee replacement, some patients received a nerve-freezing treatment (radio-frequency ablation) during the operation to reduce pain afterward. The goa…