POST OPERATIVE PAIN
Clinical trials for POST OPERATIVE PAIN explained in plain language.
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Freezing nerves before knee surgery may cut opioid need
Symptom relief OngoingThis study tests whether freezing specific nerves around the knee before total knee replacement surgery can lower pain and the need for opioids afterward. One hundred adults scheduled for knee replacement will either receive the nerve-freezing treatment or a sham procedure. Resea…
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: Esbjerg Hospital - University Hospital of Southern Denmark • Aim: Symptom relief
Last updated Jun 23, 2026 12:00 UTC
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Can sticky tape speed up shoulder surgery recovery?
Symptom relief OngoingThis study looks at whether adding kinesio taping to standard physical therapy helps people recover better after arthroscopic rotator cuff repair. Fifty adults aged 18 to 70 who had surgery for a torn rotator cuff will be randomly assigned to get either standard rehab alone or st…
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: Olcay Yavuz • Aim: Symptom relief
Last updated Jun 23, 2026 11:58 UTC
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Which pain block works best for hip surgery? new study aims to find out
Symptom relief OngoingThis study compares two types of nerve blocks (SFIB and PENG) to see which one provides better pain relief after hip replacement surgery. Sixty adults having hip surgery will be randomly assigned to receive one of the blocks. The main goal is to measure how much morphine they nee…
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: Balikesir University • Aim: Symptom relief
Last updated Jun 22, 2026 12:09 UTC
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New combo pain therapy aims to cut opioid use after hip and knee replacements
Symptom relief ENROLLING_BY_INVITATIONThis study compares two pain management approaches after total knee or hip replacement: a combination of tramadol and oxycodone versus oxycodone alone. The goal is to see if the combination reduces the total amount of opioids needed and improves pain control with fewer side effec…
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 22, 2026 12:05 UTC
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Painkiller study pulled before it even started
Symptom relief TerminatedThis study aimed to see if a tiny dose of buprenorphine/naloxone (a medicine used for opioid addiction) could help control pain after surgery in people who already take strong painkillers. It was designed for adults having orthopedic or general surgery. However, the study was wit…
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 18, 2026 11:53 UTC
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Which root canal filler hurts less? new study investigates.
Symptom relief OngoingThis study looks at 80 adults needing root canals on front teeth with small infections. It compares two different medicines placed inside the tooth between visits to see which one causes less pain and helps the bone heal better. Participants record their pain levels for a week an…
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: Ege University • Aim: Symptom relief
Last updated Jun 16, 2026 12:50 UTC
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Which drug makes nose surgery recovery less painful?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether adding dexamethasone or dexmedetomidine to a standard numbing medicine (bupivacaine) can provide longer pain relief after rhinoplasty (nose job). 90 adults having nose surgery will receive one of these combinations as a nerve block. The main goal is to se…
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE1 • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 16, 2026 12:48 UTC
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Nerve block may ease thyroid surgery pain and cut opioid use
Symptom relief OngoingThis study tests whether a numbing injection in the neck (bilateral superficial cervical plexus block) plus local wound numbing can lower pain, nausea, and the need for strong painkillers after thyroid surgery. About 74 adults having a partial or total thyroid removal will take p…
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Jun 15, 2026 18:57 UTC
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Nerve block may boost mastectomy recovery, study says
Knowledge-focused OngoingThis study looks at how well women recover after mastectomy surgery. Some women receive a PECS nerve block with a long-lasting painkiller, while others do not. Researchers want to see if the block leads to better pain control and recovery quality 72 hours after surgery. About 800…
Matched conditions: POST OPERATIVE PAIN
Sponsor: Endeavor Health • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:06 UTC