POST OPERATIVE PAIN
Clinical trials for POST OPERATIVE PAIN explained in plain language.
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New combo drug approach aims to cut opioid use after joint surgery
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether taking two pain medicines (tramadol and oxycodone) together works better than taking oxycodone alone after knee or hip replacement surgery. The goal is to see if the combination reduces the total amount of opioids needed and lowers side effects. About …
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 09, 2026 05:18 UTC
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Pain relief study for opioid users pulled before it started
Symptom relief TerminatedThis study aimed to see if a tiny dose of buprenorphine/naloxone could help manage pain after surgery in people who already take strong painkillers. It planned to compare pain scores, opioid use, and hospital stay length between the micro-dose group and standard care. However, th…
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 08, 2026 12:04 UTC
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Nose job pain relief showdown: which drug works longer?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether adding dexamethasone or dexmedetomidine to a standard numbing medicine (bupivacaine) can provide longer pain relief after rhinoplasty (nose job). About 90 adults undergoing nose surgery will receive one of these combinations as a nerve block. The main goa…
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE1 • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 08, 2026 12:03 UTC