PERIODONTAL DISEASES
Clinical trials for PERIODONTAL DISEASES explained in plain language.
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Own blood gel tested to speed gum surgery recovery
Disease control CompletedThis study tested if adding a special gel made from a patient's own blood (called L-PRF) during gum disease surgery would help the gums heal better and cause less pain after the procedure. It compared two standard surgical approaches in 21 patients with gum disease, using a 'spli…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Disease control
Last updated Apr 01, 2026 23:11 UTC
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Special gum tested to fight gum disease and boost heart health
Disease control CompletedThis study tested whether a chewing gum containing dietary nitrate (a compound found in vegetables like beets) could improve gum health and heart health. For three weeks, adults with mild to moderate gum irritation chewed either the special gum or a placebo gum. Researchers measu…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Scientists test Zinc-Infused bone graft to rebuild jawbone lost to gum disease
Disease control CompletedThis study tested whether a new bone graft material, enhanced with zinc and combined with a patient's own concentrated healing factors (platelet-rich fibrin), could help regrow bone lost to severe gum disease (periodontitis). Thirty adult patients with healthy gums but deep bone …
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Suez Canal University • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New gum surgery technique aims to rebuild lost bone
Disease control CompletedThis study tested a specific gum surgery technique combined with a protein gel to treat deep bone loss caused by severe gum disease. Seventeen adults with advanced gum disease received the surgery. Researchers tracked improvements in gum health, pocket depth, and bone regrowth ov…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Phạm Đình Thiên Khải • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Your old tooth could help your new implant heal better
Disease control CompletedThis study tested a new method to help bone heal around dental implants placed right after a tooth is pulled. Researchers compared using a processed piece of the patient's own extracted tooth as a bone graft material against a standard method. The goal was to see if this approach…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Shining a light on gum disease: can light therapy boost standard treatment?
Disease control CompletedThis study tested whether adding a special light therapy to the standard deep cleaning for gum disease improves results. Researchers compared the standard cleaning alone to cleaning plus the light treatment in 20 patients. They measured changes in gum bleeding, pocket depth, and …
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Bee product tested as gum disease fighter in young adults
Disease control CompletedThis study tested whether lozenges containing propolis, a natural resin from bees, could help control gum inflammation and plaque buildup over one week. It involved 100 young adults (ages 19-24) with moderate gum inflammation. Half used the propolis lozenges twice daily along wit…
Matched conditions: PERIODONTAL DISEASES
Phase: PHASE1 • Sponsor: Al-Mustansiriyah University • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Can switching from cigarettes to vapes give you a healthier smile?
Disease control CompletedThis study looked at whether smokers who switch to e-cigarettes or heated tobacco products see improvements in their gum health and teeth appearance. It followed 460 adult smokers and non-smokers for 18 months, comparing those who kept smoking, those who switched to smoke-free al…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Eclat Srl. • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Could a dental laser help heal hearts? study tests gum treatment for heart attack survivors
Disease control CompletedThis study tested if a special laser treatment for gum disease could help control inflammation in the body, especially for people who have had a recent heart attack. Researchers compared standard gum cleaning with cleaning plus laser therapy. They measured gum health and blood ma…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Pomeranian Medical University Szczecin • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New gel challenges standard mouthwash in fight against gum disease
Disease control CompletedThis study aimed to see if a hyaluronic acid gel works as well as a standard chlorhexidine mouthwash for managing gum disease at home. Forty patients with gum disease received a professional cleaning and were then randomly assigned to use either the gel or the mouthwash for 15 da…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: University of Pavia • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Could a daily probiotic lozenge fight gum disease?
Disease control CompletedThis study tested whether a daily probiotic lozenge could improve gum health in adults with severe periodontal disease. Fifty-five participants took the probiotic to see if it reduced gum bleeding, pocket depth, and inflammation. The goal was to see if this simple treatment could…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: TCI Co., Ltd. • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Gentle gum surgery tested to halt bone loss
Disease control CompletedThis study tested a gentle surgical technique for treating bone loss caused by advanced gum disease. It compared the surgery alone to the surgery combined with special proteins and a bone graft material. The goal was to see which approach was better at reducing deep gum pockets a…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Rungta College of Dental Sciences and Research • Aim: Disease control
Last updated Mar 11, 2026 14:54 UTC
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Dental breakthrough? study tests new gum repair methods
Disease control CompletedThis study compared three different gum surgery approaches for treating deep bone loss around teeth. Researchers tested whether adding special proteins and bone graft materials to a gentle surgical technique worked better than the technique alone. The goal was to see which method…
Matched conditions: PERIODONTAL DISEASES
Phase: PHASE4 • Sponsor: Rungta College of Dental Sciences and Research • Aim: Disease control
Last updated Mar 05, 2026 13:59 UTC
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Spit test for gum disease? researchers hunt for new diagnostic clues
Diagnosis CompletedThis study aimed to find out if measuring three specific substances in saliva could help doctors better diagnose gum disease. Researchers compared saliva samples from 60 healthy people, people with mild gum inflammation (gingivitis), and people with more serious gum disease (peri…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Izmir Katip Celebi University • Aim: Diagnosis
Last updated Mar 24, 2026 12:01 UTC
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Scientists search for clues connecting gut and gum disease
Knowledge-focused CompletedThis study aimed to understand if there is a connection between stomach inflammation (gastritis) and gum disease. Researchers compared the types of bacteria in the saliva of 30 people with gastritis to those of healthy individuals. They used advanced lab tests to see if the bacte…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Aydin Adnan Menderes University • Aim: Knowledge-focused
Last updated Apr 01, 2026 23:11 UTC
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Do future dentists have healthier teeth than future doctors?
Knowledge-focused CompletedThis study aimed to understand if dental and medical students have different levels of gum and tooth health, and how that affects their daily lives. Researchers examined 400 healthy undergraduate students, checking for plaque, gum inflammation, cavities, and asking about their or…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Recep Tayyip Erdogan University Training and Research Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 23:11 UTC
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Could your gums hold a clue to your heart health?
Knowledge-focused CompletedThis study looked for a link between gum health and a substance in the blood linked to heart disease risk. Researchers measured this substance in the blood and saliva of 61 people with clogged leg arteries. They compared levels between people with healthy gums, gum disease, or no…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Ankara University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Smokers' gums: study reveals hidden damage
Knowledge-focused CompletedThis study aimed to understand how smoking affects gum health. Researchers compared 484 adults, split evenly between current smokers and non-smokers, by measuring their plaque, gum bleeding, and gum disease severity. The goal was to gather data on the relationship between smoking…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Tuğba ŞAHİN • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists search for gum disease clues in spit
Knowledge-focused CompletedThis study aimed to understand gum disease better by measuring the levels of three specific proteins in saliva. Researchers collected saliva samples from 60 people with healthy gums, gingivitis, or periodontitis to see if protein levels correlated with the health of their gums. T…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Izmir Katip Celebi University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists find chemical clue linking gum health to brain disease
Knowledge-focused CompletedThis study aimed to understand if there is a biological connection between gum disease (periodontitis) and Parkinson's disease. Researchers compared saliva and blood samples from 60 people across three groups: those with both conditions, those with just gum disease, and healthy i…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Medipol University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists search for gum disease clues in spit
Knowledge-focused CompletedThis study aimed to understand the role of a protein called IL-36α in gum disease. Researchers collected saliva and fluid from the gums of 80 people, including those with healthy gums, gingivitis, and periodontitis. They measured the protein levels and compared them to standard d…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Ordu University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Scientists search for hidden gum disease in bridge patients
Knowledge-focused CompletedThis study aimed to better understand gum health in people who need fixed dental bridges. Researchers measured specific inflammation markers in the gum fluid of 90 patients to detect early signs of gum disease that might not be visible during a regular dental check-up. The goal w…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Jagiellonian University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Could better dental care ease hidden inflammation in HIV?
Knowledge-focused CompletedThis study aimed to understand the connection between oral health and long-term health issues in people living with HIV. Researchers followed 227 adults with HIV on stable medication for about 2.5 years, checking their dental health, collecting samples, and measuring inflammation…
Matched conditions: PERIODONTAL DISEASES
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Could ancient wheat fight gum disease and cancer risk?
Knowledge-focused CompletedThis small, completed study explored whether adding an ancient type of wheat called einkorn to people's diets could change the balance of bacteria in their mouths. Researchers measured bacteria linked to gum disease and general health markers in 31 healthy adults before and after…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Could your morning coffee affect your gums?
Knowledge-focused CompletedThis completed study aimed to find out if how often and how people drink coffee is connected to the health of their gums. Researchers observed 318 adults, grouping them by gum health status, and recorded their detailed coffee habits. They then looked for links between these habit…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Tuğba ŞAHİN • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Scientists search for gum disease clues in your Mouth's fluid
Knowledge-focused CompletedThis study aimed to understand gum disease better by measuring two specific proteins in the fluid around the gums. It involved 99 adults with healthy gums, mild gum inflammation (gingivitis), or more serious gum disease (periodontitis). All participants with gum issues received a…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Cumhuriyet University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Scientists probe surprising link between skin and gum health
Knowledge-focused CompletedThis study aimed to understand if there is a connection between psoriasis, a chronic skin condition, and the health of a person's gums. Researchers compared 226 people with psoriasis to a group without it, checking their oral health and asking about their quality of life. The goa…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Could cleaning your teeth calm your joints? study probes Gum-Joint link
Knowledge-focused CompletedThis study aimed to better understand the link between gum disease (periodontitis) and rheumatoid arthritis. Researchers measured specific antibodies in the gums of 36 patients with both conditions before and after a standard gum cleaning treatment. The goal was to see if improvi…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Misr International University • Aim: Knowledge-focused
Last updated Mar 11, 2026 14:54 UTC
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Scientists put teeth under the microscope to find smoothest polish
Knowledge-focused CompletedThis study aimed to find the best way to polish teeth after a professional cleaning to keep them smooth and prevent plaque buildup. Researchers tested three common polishing methods on 56 extracted human teeth and examined the surface smoothness under a powerful microscope. The g…
Matched conditions: PERIODONTAL DISEASES
Phase: NA • Sponsor: Khyber Medical University Peshawar • Aim: Knowledge-focused
Last updated Mar 11, 2026 14:53 UTC
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Scientists probe why gum treatment works differently for men and women
Knowledge-focused CompletedThis study aimed to understand how a standard, non-surgical gum cleaning treatment affects the body's immune response. Researchers followed 100 people with gum disease, comparing men and women, and those with and without obesity, to see if treatment worked differently for them. T…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Milagros Rocha Barajas • Aim: Knowledge-focused
Last updated Mar 10, 2026 12:53 UTC
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Better dental knowledge linked to healthier gums, study finds
Knowledge-focused CompletedThis completed study looked at whether people's understanding of oral health affects their gum health. Researchers examined 108 adults in Turkey, measuring their dental knowledge and checking their gums. The goal was to see if lower health knowledge is connected to worse gum dise…
Matched conditions: PERIODONTAL DISEASES
Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Mar 03, 2026 14:06 UTC