PERIODONTAL DISEASES

This study tested a new way to repair bone gaps that can happen when a dental implant is placed right after a tooth is pulled. Researchers used a plate made from the patient's own tooth to cover the gap, along with a tooth graft. The trial included 63 adults aged 20 to 45 who nee…

This study tested whether a probiotic called TCI188 could improve oral health in 55 adults with severe gum disease. Researchers measured changes in gum pocket depth and bleeding. The goal was to see if the probiotic helps control gum disease symptoms.

This study tested whether adding enamel matrix derivative and a bone graft to a less invasive gum surgery helps repair bone loss between teeth better than surgery alone. Forty-five adults with gum disease and at least one deep pocket took part. Researchers measured pocket depth a…

This study tested whether adding antimicrobial photodynamic therapy (aPDT) — a treatment that uses light to kill bacteria — to standard deep cleaning improves outcomes for people with gum disease. Twenty adults with deep gum pockets and bleeding participated. Researchers measured…

This study tested whether a chewing gum containing dietary nitrate (like in leafy greens and beets) could improve gum health and heart health in adults with mild gum disease. Thirty participants were randomly assigned to use either the nitrate gum or a placebo gum for three weeks…

This study looked at how different types of small brushes for cleaning between teeth (interdental brushes) affect gum health in young adults aged 18 to 30. The goal was to see if brushes that are sized to fit each person's gaps (calibrated) work better than one-size-fits-all brus…

This study tested a gum surgery technique (EPPT) alone or with enamel matrix derivative and bone graft material to repair bone damage from gum disease. 58 adults with moderate to severe gum disease and isolated bone defects participated. The goal was to see if adding these materi…

This study looked at whether using a 980nm diode laser along with standard deep cleaning improves gum health and reduces body-wide inflammation in people with gum disease, including those who had a heart attack in the last 6 months. About 80 participants under 70 years old were d…

This study tested whether a hyaluronic acid gel or a chlorhexidine mouthwash works better as a follow-up treatment after deep cleaning for gum disease. Forty adults with periodontitis used one of the two products at home for 15 days. Researchers measured gum pocket depth, bleedin…

This study tested a gum surgery that combines a connective tissue graft with an enamel matrix protein to help regrow bone and soft tissue in people with advanced gum disease. Seventeen adults with deep gum pockets received the treatment, and researchers measured improvements in b…

This study tested whether lozenges made from propolis (a bee product) could reduce gum inflammation and plaque in 100 adults aged 19–24 with moderate gingivitis. Participants used the lozenges for one week, while a control group only received oral hygiene instructions. Researcher…

This study looked at whether smokers who switch to combustion-free nicotine delivery systems (like e-cigarettes or heated tobacco) see improvements in gum health and tooth appearance compared to those who keep smoking or never smoked. About 460 healthy adults took part, and resea…

This study tested whether a special bone graft material made with zinc and a blood-clot block can help repair bone damage caused by gum disease. Thirty adults with gum disease received the treatment, and researchers measured gum health and bone levels. The goal was to see if thes…

This study looked at whether three substances found in saliva—HIF-2 alpha, MMP-9, and TRAP-5b—can help tell the difference between healthy gums, gingivitis (mild gum inflammation), and periodontitis (serious gum disease). Researchers measured these substances in 60 adults who wer…

This study tested whether adding a substance made from a patient's own blood (L-PRF) to standard gum surgery improves healing and reduces pain. 21 adults with gum disease had two areas treated: one with standard surgery and one with the added L-PRF. Researchers measured pocket de…

This study tested a special ultrasonic tool that uses hydroxyapatite (a natural enamel-like substance) to reduce tooth sensitivity during gum disease maintenance. 40 adults with advanced gum disease received standard treatment on one side of the mouth and the new tool on the othe…

This study examined the relationship between coffee consumption and gum health in 318 adults aged 18 to 65. Participants were grouped by gum condition (healthy, gingivitis, or periodontitis), and their coffee habits—including frequency, amount, and additives—were recorded. Resear…

This study examined 293 Egyptian adults with multiple sclerosis to see how common gum disease is in this group. Researchers performed a standard dental exam to measure gum health. The goal was to find out if there is a link between MS and periodontal disease. No treatment was giv…

This study looked at whether people with psoriasis have worse gum health and how it affects their quality of life. Researchers compared 226 adults with and without psoriasis through mouth exams and questionnaires. The goal was to understand the link between psoriasis and oral hea…

This completed study looked at 100 people with gum disease, some with obesity and some without, to see how non-surgical gum cleaning affects the body's immune system. Researchers compared men and women to find differences in immune response and looked for tiny molecules called mi…

This study looked at 99 adults with healthy gums, gingivitis, or periodontitis to see how non-surgical gum cleaning changes two proteins (Dkk-1 and sFRP5) in the fluid around teeth. Researchers measured these proteins before and after treatment to understand their link to gum inf…

This study looked at 56 extracted human teeth to see how three different polishing methods—bristle brush, rubber cup, and air polishing—affect tooth surface roughness after scaling. The goal was to find which method leaves teeth smoothest to help prevent plaque buildup. Researche…

This study looked at 60 people to see if gum disease (periodontitis) and Parkinson's disease share a biological connection through inflammation. Researchers measured certain substances in saliva and blood related to tryptophan, a natural amino acid. They found higher levels of so…

This study looked at a protein called pentraxin in the gum fluid of teeth that support fixed dentures. The goal was to find early signs of gum disease that are not visible during a regular checkup. 90 adults who needed fixed dentures and had no visible gum inflammation took part.…

This study looked at 400 dental and medical students to see if their oral health affects their quality of life. Researchers checked for gum disease, cavities, and other dental problems, and asked students how they feel about their oral health. The goal was to understand the link …

This study looked at 108 Turkish adults to see if knowing more about oral health leads to healthier gums. Participants took a reading test about dental terms and got a gum exam. The goal was to find out if people with lower oral health literacy have worse gum disease, which could…

This study looked at a protein called IL-36α in the saliva and gum fluid of 80 people with healthy gums, gingivitis, or periodontitis. Researchers wanted to see if levels of this protein differ between these groups and relate to standard measures of gum health. The goal was to be…

This study looked at whether eating einkorn, an ancient cereal, could change the types of bacteria in the mouth. Researchers focused on bacteria linked to gum disease and cancer risk. Thirty-one healthy adults added einkorn to their usual diet, and their mouth bacteria were measu…

This study examined the link between smoking and gum disease in 484 adults. Participants were divided into current smokers and non-smokers, and their gum health was measured using standard dental exams. The goal was to understand how smoking habits relate to conditions like gingi…

This study compared the types of bacteria in the mouths of 30 people with and without gastritis (stomach inflammation). Researchers used advanced DNA testing to see if people with gastritis have different mouth germs. The goal was to learn more about how stomach and gum health mi…

This study looked at whether three substances in saliva (Adseverin, 1-Alpha defensin, and sRANKL) can help tell the difference between healthy gums, gingivitis, and periodontitis. Researchers collected saliva from 60 non-smoking adults and compared the levels of these substances …

This study looked at 61 adults with peripheral artery disease to see if their gum health was linked to levels of a substance called TMAO in their blood and saliva. Researchers compared people with healthy gums, gum disease, or no teeth. The goal was to understand if oral health m…

This study looked at 36 adults with rheumatoid arthritis to see if the severity of gum disease is linked to levels of certain antibodies (ACPAs) found in gum fluid. Researchers measured these antibodies before and after non-surgical gum treatment. The goal was to better understan…

This study looked at 227 people with HIV who are on antiretroviral therapy to see if poor oral health (like gum disease and cavities) is linked to ongoing inflammation and metabolic problems. Researchers measured dental health, bone density, and quality of life. The goal was to u…