PERIODONTAL DISEASES

This study aims to see how well 3D printed, custom-fit bone grafts work for rebuilding jawbone lost to severe gum disease. It will follow 100 patients for up to six years to check if dental implants placed into the new bone remain stable and to measure how much the grafted bone s…

This study aims to see if using a special antibacterial light therapy device or an electric toothbrush at home is better than a regular manual toothbrush for improving gum health and quality of life in older adults. It will involve 90 participants aged 60+ who have gum disease an…

This study is testing whether adding a special anti-inflammatory mouthwash to a deep cleaning treatment works better for advanced gum disease. Twenty adults with severe gum disease will receive the deep cleaning and be randomly assigned to use either the active mouthwash or a pla…

This study aims to see if a short, self-reported questionnaire can accurately identify gum disease in adults. Participants will fill out the questionnaire and then receive a standard dental exam during the same visit. Researchers will compare the questionnaire answers to the exam…

This study aims to see if easier methods—like taking photos with a smartphone, answering a questionnaire, or using dental X-rays—can accurately detect gum disease. It will compare these methods to a full dental exam, which is the current best way to check. Researchers will use ar…

This study aims to test and improve a short questionnaire designed to screen for periodontitis (severe gum disease). About 495 patients at dental clinics across Italy will fill out the questionnaire and then receive a full dental exam. Researchers will compare the questionnaire a…

This study is testing a new online questionnaire designed to help people check their own risk for gum disease. About 400 adults will answer the questions and then get a professional dental exam during the same visit. Researchers will compare the results to see if the online tool …

This study is developing a new, non-invasive test for periodontitis (gum disease) using a small sensor that analyzes saliva. Researchers will collect saliva samples from about 200 adults, some with gum disease and some without, to train an AI system to spot disease patterns. The …

This study aims to find out if tiny plastic particles, called microplastics, are present in the gums of people with severe gum disease (periodontitis). Researchers will collect plaque samples from 25 adults who have not yet started treatment. The goal is to see if these environme…

This study aims to understand if teeth that handle more chewing force are more likely to have severe gum disease. Researchers will use special software to measure bite pressure and compare it to the health of the gums and bone around the teeth. The goal is to gather knowledge, no…

This study aims to gather detailed information about the dental, facial, and oral health of people with Mowat-Wilson Syndrome (MWS), a rare genetic condition. Researchers will examine 25 participants and ask their caregivers questions to understand their quality of life related t…

This study aims to find out if measuring certain substances in saliva can predict a person's gum health two years later. Researchers will follow 100 adults, some with healthy gums and some with gum disease, checking their health and collecting saliva samples over two years. The g…

This study aims to understand if a standard Parkinson's disease medication (Levodopa-Benserazide) has any effect on gum health and inflammation. Researchers will compare gum health and saliva samples from 136 people across four groups: those with Parkinson's and gum disease, thos…

This study aims to find early warning signs in saliva and gum fluid that could help dentists spot and monitor disease around dental implants (peri-implantitis) sooner. Researchers will compare samples from 80 people with healthy gums, gum disease, or implant disease. The goal is …

This study aims to find out which of three common dental techniques is best for gently shaving small amounts of enamel from between teeth during clear aligner treatment. Researchers will compare how accurately each method removes the planned amount of tooth material and check for…

This study aims to find out if people with multiple sclerosis (MS) are more likely to have gum disease. Researchers will examine the mouths of about 300 Egyptian adults who already have MS. The goal is to see if there is a connection between the two conditions, which could help d…

This study aims to understand the connection between severe gum disease and heart health. Researchers will compare levels of a specific substance (oxidized LDL) in the fluid from the gums of 40 healthy people and people with advanced gum disease. The goal is to see if this substa…