PERIODONTAL DISEASES

This study tests whether a special light device used at home or a powered toothbrush can improve gum health and bad breath in older adults (60+) who have gum disease and mild memory issues. Ninety participants will be split into three groups: one using the light device plus a man…

This study looks at how well 3D-printed, custom-fit bone grafts work for rebuilding jawbone lost to gum disease. Researchers will check if dental implants placed in the grafted area stay stable and measure how much the graft shrinks over time. The study involves 100 healthy adult…

This study aims to validate an Italian version of a widely used gum disease screening questionnaire and develop an improved version with extra questions. Researchers will enroll 495 adults across 10 Italian centers to see how accurately the questionnaire identifies people with pe…

This study will check if simple methods like mouth photos, dental X-rays, and health questionnaires can accurately find gum disease compared to a full dentist exam. About 2,000 adults will take part, and the results will help create AI tools for faster, easier screening. The goal…

This study aims to see if a self-reported questionnaire can accurately identify gum disease (periodontitis or gingivitis) in adults. About 291 participants in Saudi Arabia will fill out the questionnaire and then receive a standard dental exam on the same visit. Researchers will …

This study is developing a new, non-invasive test for gum disease (periodontitis) using a saliva sample and artificial intelligence. Researchers will collect saliva from 200 adults—some with gum disease and some healthy—to train an AI to spot the disease early. The goal is to cre…

This study aims to develop and validate an online self-assessment tool for periodontal (gum) disease risk. About 393 adults in Saudi Arabia will complete a questionnaire and then receive a clinical dental exam to see how well the tool matches professional diagnosis. The goal is t…

This study tests a new program that teaches pregnant women in Bangladesh how to care for their teeth and gums during their regular prenatal visits. Over 95% of pregnant women in Bangladesh have gum disease, but oral health is not usually part of pregnancy care. The study will com…

This study looks at whether using a special anti-inflammatory mouthwash after a deep dental cleaning can improve healing for people with advanced gum disease. About 20 adults with deep gum pockets will either get the active mouthwash or a placebo, and their gum health will be tra…

This study follows 100 adults with healthy gums or various stages of gum disease for two years. Researchers will collect saliva and plaque samples to see if certain markers can predict who will get worse. No treatment is given—the goal is simply to learn which biomarkers signal f…

This study will look at the teeth, mouth, face, and quality of life of 25 people with Mowat-Wilson syndrome, a rare genetic condition. Researchers will measure things like cavities, jaw alignment, and facial shape using photos and scans. The goal is to better understand the denta…

This study looks at three different methods dentists use to remove a tiny bit of enamel between teeth to make room for clear aligners. Seventy-five adults getting clear aligners will be randomly assigned to one of the three techniques. The main goal is to see which method is most…

This study will measure certain proteins and stress markers in saliva and fluid around dental implants and teeth. Researchers want to see if these markers can help detect and track bone destruction in people with peri-implantitis or periodontitis. 80 healthy volunteers and patien…

This study looks at whether people with severe gum disease have higher levels of a certain oxidized fat (oxLDL) in their gum fluid compared to those with healthy gums. Researchers will collect gum fluid from 40 adults aged 30-60 to measure oxLDL levels. The goal is to better unde…

This study looks at 108 adults aged 30-65 to see how certain genes, mouth bacteria, and viruses relate to gum disease and heart problems. Researchers will measure changes in gum health and check for specific germs and a gene called klotho. The goal is to better understand the con…

This study aims to find out if tiny plastic particles, called microplastics, are present in the deep gum pockets of people with severe gum disease (periodontitis). Researchers will collect plaque samples from 25 adults who have not yet started treatment. The goal is to see if the…

This study looks at whether teeth that bear more chewing force are more likely to have gum disease. Researchers will measure bite patterns in 50 adults and compare them to gum health. The goal is to understand if uneven chewing loads contribute to gum problems.