PERIODONTAL DISEASES

This study aims to see if using a sodium bicarbonate (baking soda) fluoride toothpaste daily helps keep gums healthy after a professional dental cleaning. Researchers will follow 100 adults for six months, giving them either the test toothpaste or a placebo. They will check gum h…

This study aims to find out which type of interdental brush (flossing tool) works better for daily gum care in young adults. Researchers are comparing specially sized brushes against regular ones to see which reduces gum bleeding and harmful bacteria more effectively over three m…

This study is testing whether adding an injectable gel made from a patient's own blood (i-PRF) to a standard cow bone graft works better than the graft alone for treating severe gum disease. The goal is to help regrow bone lost around teeth and improve gum health. Researchers wil…

This study is testing if adding a lovastatin gel under the gums improves the results of standard deep cleaning for periodontal disease. It will compare the gel to a placebo in 44 adults, including both smokers and non-smokers. Researchers will measure gum health over six months t…

This study is testing a new gum surgery technique for people with advanced gum disease. The new method makes a single cut between teeth to better preserve the body's natural healing tissue. Researchers will compare this new approach to a standard surgery to see if it leads to bet…

This study is comparing two brands of dissolvable stitches (Novosyn Quick and Monosyn Quick) to see if they work equally well for healing after gum surgery. Researchers will measure how well the wounds close, check for pain and swelling, and ask patients about their satisfaction.…

This study is testing whether a 6-month telehealth program using smartphones can help cancer survivors prevent painful mouth sores and gum disease, improve their quality of life, and reduce body-wide inflammation. It will compare this program to usual care in 100 cancer survivors…

This study compares two surgical methods for treating bone loss caused by advanced gum disease. Researchers will test a new collagen matrix material against a standard bone graft material in 80 patients over 12 months. The goal is to see which approach better helps gums reattach …

This study is testing whether adding a new dental gel to the standard deep cleaning treatment works better for adults with moderate gum disease. The gel is used daily at home and aims to reduce deep pockets around the gums more than the standard treatment alone. Researchers will …

This study is testing if using a high-magnification digital microscope during gum surgery leads to better healing than the current standard tool, magnifying loupes. Researchers will compare healing in 25 adults who need surgery for gum disease. Each participant will have one inci…

This study tests a new system in primary care clinics to help older adults on Medicaid get to the dentist. Medical assistants will be trained to screen for oral health problems and make referrals during regular doctor visits. Researchers want to see if this approach leads to more…

This study is comparing three different surgical techniques for treating advanced gum disease (periodontitis). It will involve 60 patients with deep gum pockets and bone loss. The goal is to see which surgical approach is most effective at reducing pocket depth, improving gum att…

This study aims to find simple markers in blood and saliva that can predict how well people with gum disease will heal after standard cleaning treatment. Researchers will observe 180 adults with healthy gums, gingivitis, or serious periodontitis, taking samples before and after t…

This study aims to understand if there is a connection between how severe a person's Pemphigus Vulgaris (a chronic autoimmune skin disease) is and the health of their gums. Researchers will examine 20 adult patients with the condition, checking their mouth sores and measuring spe…

This study aims to understand how gum tissue heals differently in people with severe gum disease, particularly comparing smokers and non-smokers. Researchers will collect small tissue samples during routine gum surgery from 46 participants to analyze healing properties and bacter…