Could a Blood-Derived gel help rebuild bone lost to gum disease?
NCT ID NCT07146776
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether adding injectable platelet-rich fibrin (i-PRF) to a standard bone graft helps fill in bone defects caused by advanced gum disease. Sixteen adults with stage III periodontitis will receive either the combo treatment or the graft alone during surgery. Researchers will measure bone fill and gum attachment levels over six months to see if the i-PRF makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
injectable platelet-rich fibrin (i-PRF) mixed with bovine bone graft
What this could lead to
If it works, this could point toward a better way to repair bone defects caused by gum disease, potentially improving tooth stability.
What could go wrong
This is a very small early trial (16 people) with no blinding, so results may not be reliable or generalizable. The procedure is surgical and carries typical risks like infection or pain.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sağlık Bilimleri Üniversitesi
RECRUITINGIstanbul, Üsküdar, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••