Gum healing boost? scientists test hyaluronic acid and polynucleotides

NCT ID NCT06309719

Recruiting now Knowledge-focused Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This pilot study investigates how a gel made from hyaluronic acid and polynucleotides affects early healing of gum defects after surgery. Researchers will measure molecular markers in gum fluid and use laser imaging to track blood flow changes. The study includes 24 adults with advanced gum disease who will receive either standard surgery or surgery plus the gel.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hyaluronic acid and polydeoxyribonucleotides gel
What this could lead to: If successful, this could point toward a better way to treat gum disease by improving early healing after surgery.
What could go wrong: This is a small pilot study with only 24 participants, so results may not apply to everyone. The treatment is experimental and may not improve healing over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Periodontal Attachment Loss periodontal disorder Periodontal Pocket periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL ATTACHMENT LOSS PERIODONTAL DISEASES PERIODONTAL INFLAMMATION PERIODONTAL POCKET WOUND HEAL

Contacts and locations

Locations

Barts Health NHS Trust Dental Hospital
RECRUITING

London, E1 1BB, United Kingdom
Centre for Oral Clinical Research (COCR)
RECRUITING

London, E1 2AD, United Kingdom

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