MENOPAUSE
Clinical trials for MENOPAUSE explained in plain language.
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New light probe offers hope for menopausal vaginal discomfort
Symptom relief CompletedThis early study tested a new vaginal probe that uses special lights (photobiomodulation) to help postmenopausal women with vaginal atrophy that hasn't improved with other treatments. The probe aims to stimulate natural tissue repair to reduce pain and dryness. 25 women participa…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 12:46 UTC
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Probiotic blend shows promise for menopause symptom relief
Symptom relief CompletedThis study tested whether a mix of three probiotics could improve quality of life and reduce menopause-related symptoms in women going through or just past menopause. 245 women aged 45-60 took either the probiotic or a placebo daily. Researchers used questionnaires to measure cha…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: AB Biotics, SA • Aim: Symptom relief
Last updated May 17, 2026 12:45 UTC
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Gut health hack for hot flushes? new study tests polyphenols & probiotics
Symptom relief CompletedThis study tested whether a combination of polyphenols (plant compounds) and probiotics (good bacteria) can improve menopause symptoms like hot flushes, low mood, and sleep problems. Thirty postmenopausal women took part. The idea is that these supplements may help balance gut ba…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University of Roehampton • Aim: Symptom relief
Last updated May 17, 2026 12:43 UTC
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Self-Compassion classes show promise for menopause mood swings
Symptom relief CompletedThis study looked at whether group compassionate mind training (CMT) is a practical and helpful way to support adults going through menopause. 38 women aged 40-60 took part, learning skills to reduce self-criticism and increase self-compassion. The goal was to see if this approac…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated May 17, 2026 12:42 UTC
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Game on for menopause: interactive sleep training boosts quality of life
Symptom relief CompletedThis study tested a new approach: teaching menopausal women about good sleep habits through an interactive game instead of a boring lecture. 82 women with poor sleep quality played the game and researchers measured changes in their sleep, menopause symptoms, and overall well-bein…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Meryem Vural Şahin • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Laughter yoga eases menopause symptoms, study finds
Symptom relief CompletedThis study tested whether laughter yoga can help manage menopause symptoms and improve quality of life. 120 postmenopausal women took part. The approach involved regular laughter yoga sessions, and the researchers measured changes in symptoms and well-being using standard questio…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Estrogen therapy may soothe bladder troubles by altering urine microbiome
Symptom relief CompletedThis study looked at whether a low-dose vaginal estrogen tablet could improve overactive bladder symptoms in menopausal women by changing the bacteria in their urine. Thirty women used the estrogen daily for two weeks, then twice a week for 12 weeks. Researchers measured changes …
Matched conditions: MENOPAUSE
Phase: PHASE4 • Sponsor: Mahidol University • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Can a wellness supplement ease perimenopause? 500 women put it to the test.
Symptom relief CompletedThis study tested a health and wellness product in 500 perimenopausal women aged 40 and older to see if it could improve stress, sleep, and menopause-related issues. Participants took either the product or a placebo, and researchers measured changes in perceived stress and other …
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Radicle Science • Aim: Symptom relief
Last updated May 14, 2026 12:01 UTC
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Can a simple injection ease menopause pain? new study says maybe
Symptom relief CompletedThis small study tested whether injecting a gel-like substance (hyaluronic acid) into the vaginal area could help menopausal women with pain during sex. Twenty women received the injections and were followed for 8 weeks. The main goal was to see if the vaginal lining thickened, w…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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New brain training shows promise for menopause fog
Symptom relief CompletedThis study tested a cognitive intervention designed to help with 'brain fog'—memory and concentration problems—during menopause. It included 33 women aged 40-60 who reported these issues. The goal was to see if the program was practical and helpful, not to prove it works yet.
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Natural brain chemical may ease menopausal depression
Symptom relief CompletedThis study tested whether a natural steroid called pregnenolone can reduce depression in women going through menopause or perimenopause. 73 women received either pregnenolone or a placebo. The goal was to see if it improves mood, anxiety, thinking, and quality of life. The study …
Matched conditions: MENOPAUSE
Phase: PHASE1, PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated May 11, 2026 20:52 UTC
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Sleep pill shows promise for menopausal Women's heart and sugar health
Symptom relief CompletedThis study tested whether the sleep drug suvorexant could reduce insomnia severity and improve metabolic health in 31 midlife women (ages 40-65) who had insomnia and signs of metabolic syndrome. Participants took the medication for 4 weeks. The goal was to see if better sleep cou…
Matched conditions: MENOPAUSE
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated May 11, 2026 20:49 UTC
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Laughter yoga eases menopause brain fog, study finds
Symptom relief CompletedThis study tested whether laughter therapy could help women in menopause with brain fog, mood, and sleep. 97 women who had gone through natural menopause in the last 3 years took part. They did 8 sessions of laughter yoga over 4 weeks, including deep breathing, warm-ups, and play…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Agri Ibrahim Cecen University • Aim: Symptom relief
Last updated May 08, 2026 12:01 UTC
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New drug shows promise for menopause hot flashes in early trial
Symptom relief CompletedThis study tested a new medicine called NOE-115 in 40 women aged 45 to 60 who have moderate to severe hot flashes due to menopause. The goal was to see if the drug is safe and if it can reduce hot flashes. Participants took the drug for 4 weeks, and researchers monitored side eff…
Matched conditions: MENOPAUSE
Phase: PHASE2 • Sponsor: Noema Pharma AG • Aim: Symptom relief
Last updated May 06, 2026 16:01 UTC
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Estrogen pellet study reveals hormone release over 24 weeks
Knowledge-focused CompletedThis study looked at how a small, absorbable pellet containing 25 mg of estradiol releases the hormone into the body over 24 weeks. Twenty postmenopausal women with low estrogen levels received the pellet under the skin. Researchers took many blood samples to track estrogen level…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Science Valley Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 12:44 UTC
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Choline doses tested for brain signals in menopause
Knowledge-focused CompletedThis study looked at whether small doses of choline (550 mg and 1100 mg) can change brain activity in healthy postmenopausal women aged 50-65. Participants took choline or a placebo, and their brain signals were measured with fMRI during a memory task. The goal was to see if lowe…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Julie Dumas • Aim: Knowledge-focused
Last updated May 17, 2026 12:42 UTC
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Quercetin and statins: new clues for Women's heart health?
Knowledge-focused CompletedThis study looked at how the supplement quercetin and the statin drug atorvastatin change levels of estrogen and a protein called SIRT1 in postmenopausal women with stable coronary artery disease. Researchers measured these substances in the blood of 60 women to understand possib…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: InCor Heart Institute • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Menopause timing linked to mental health in new study
Knowledge-focused CompletedThis study looked at 136 women to see if the age they go through menopause is linked to anxiety and depression. It compared women with early menopause (before age 40) to those with natural menopause after 40. Researchers used standard questionnaires to measure anxiety levels duri…
Matched conditions: MENOPAUSE
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Menopause's hidden toll on skin revealed in new study
Knowledge-focused CompletedThis study looked at how skin ages in women going through menopause, comparing sun-exposed and non-exposed areas. Researchers tracked 100 women's skin, mood, sleep, and hot flashes over 30 days. The goal was to understand how hormonal changes affect skin and well-being, not to te…
Matched conditions: MENOPAUSE
Sponsor: ChinaNorm • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Hormone therapy may improve liver fat in menopause
Knowledge-focused CompletedThis study explored whether menopausal hormone therapy (MHT) can improve liver function and reduce fatty liver in postmenopausal women. 44 women were split into two groups: 22 received MHT and 22 did not. After 6 months, researchers measured liver fat, enzymes, and fibrosis marke…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Ipek B. Ozcivit Erkan, MD • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Brain study reveals why menopause hormones trigger irritability in some women
Knowledge-focused CompletedThis study looked at why some women in early menopause become irritable when their estrogen levels change. Forty healthy women aged 45-59 with moderate to severe irritability took either estrogen or a placebo for three weeks. Researchers measured their brain activity and mood to …
Matched conditions: MENOPAUSE
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Can exercise help menopausal women breathe easier?
Knowledge-focused CompletedThis study looked at how a structured endurance training program affects exercise tolerance in 43 postmenopausal women under 70 who had unexplained shortness of breath and were not very active. Researchers measured changes in cardiorespiratory fitness and muscle oxygenation to un…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University of Poitiers • Aim: Knowledge-focused
Last updated May 13, 2026 16:00 UTC
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Custom estrogen creams put to the test: do they match up?
Knowledge-focused CompletedThis study looked at whether two different custom-made estrogen creams deliver the same amount of hormone into the blood. Eight postmenopausal women aged 45 to 65 used the creams, and researchers measured their estrogen levels. The goal was to check quality, not to treat any cond…
Matched conditions: MENOPAUSE
Phase: EARLY_PHASE1 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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Choline boosts brain activity in menopause, study finds
Knowledge-focused CompletedThis study looked at how a single large dose of choline (a nutrient) affects brain function in 38 healthy postmenopausal women aged 50-65. Participants took either choline or a placebo, and their brain activity was measured with an MRI while they did a memory task. The goal was t…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC
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Your temperament could shape your menopause experience
Knowledge-focused CompletedThis study explored whether a woman's natural temperament—like being more anxious or upbeat—is linked to how severe her menopause symptoms feel. Researchers asked 105 women going through menopause to fill out two questionnaires about their mood and symptoms. The goal was simply t…
Matched conditions: MENOPAUSE
Sponsor: Bagcilar Training and Research Hospital • Aim: Knowledge-focused
Last updated May 06, 2026 16:13 UTC