MENOPAUSE
Clinical trials for MENOPAUSE explained in plain language.
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Can garlic and enzymes make menopause hormones safer?
Disease control CompletedThis study tested whether adding natural ingredients like garlic oil and nattokinase to standard hormone replacement therapy (HRT) could reduce the risk of blood clots in menopausal women. The trial involved 60 women divided into premenopausal and postmenopausal groups. Researche…
Matched conditions: MENOPAUSE
Phase: PHASE4 • Sponsor: Trieu, Nguyen Thi, M.D. • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Can a natural supplement boost heart drug benefits in older women?
Disease control CompletedThis completed study looked at 60 postmenopausal women with stable coronary artery disease. Researchers tested whether adding a daily 1000 mg quercetin supplement to standard atorvastatin treatment could affect levels of estrogen and a protein called SIRT1, which are linked to he…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: InCor Heart Institute • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Hemp compounds may cool menopause hot flashes and mood swings
Symptom relief CompletedThis study looked at whether hemp-derived cannabinoids can reduce menopause and perimenopause symptoms like hot flashes, anxiety, and mood swings. 104 women aged 40-60 who were not regular cannabis users took part. Researchers tracked their symptoms daily and monthly to see if th…
Matched conditions: MENOPAUSE
Phase: PHASE2 • Sponsor: Washington State University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Simple relaxation exercises may ease menopause symptoms at work
Symptom relief CompletedThis study tested whether progressive relaxation exercises can reduce menopause symptoms like hot flashes, mood swings, and sleep problems, and improve work performance. 106 women aged 45-65 who had not menstruated for a year participated. Half did relaxation exercises while the …
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Aydin Adnan Menderes University • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Gut-Brain fix for hot flushes? small study tests polyphenols & probiotics
Symptom relief CompletedThis study tested whether a combination of polyphenols (plant compounds) and probiotics (good bacteria) can improve menopause symptoms like hot flushes, low mood, and sleep trouble. Sixteen postmenopausal women took the supplement to see if it changed blood chemistry, body mass i…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University of Roehampton • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Coloring your way to better menopause? study tests mandala art therapy
Symptom relief CompletedThis study looked at whether coloring mandalas—circular, symmetrical patterns—can reduce menopause symptoms, improve self-esteem, and boost sexual quality of life in women aged 40 to 65. Seventy women who had not had a period for at least a year and had moderate to severe menopau…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Kahramanmaras Sutcu Imam University • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Talking therapy could ease menopause mood swings without hormones
Symptom relief CompletedThis study tested whether a 6-session online group program called Compassionate Mind Training (CMT) can improve wellbeing in women aged 40-60 going through menopause. The therapy aims to reduce self-criticism and shame by building self-compassion. Researchers enrolled 38 women to…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Laughter therapy shows promise for menopause brain fog
Symptom relief CompletedThis study tested whether laughter yoga could help women in menopause who struggle with brain fog, low mood, and poor sleep. 97 women were split into two groups: one did 8 sessions of laughter yoga over 4 weeks, and the other did nothing. Researchers measured brain fog, psycholog…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Agri Ibrahim Cecen University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can a sleep drug boost metabolic health in menopausal women?
Symptom relief CompletedThis study tested whether the sleep medication suvorexant (Belsomra) can reduce insomnia severity and improve metabolic health in midlife women who have both insomnia and signs of metabolic syndrome. Thirty-one healthy women aged 40-65 who were perimenopausal or postmenopausal to…
Matched conditions: MENOPAUSE
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Vaginal estrogen may ease bladder troubles by altering urine microbiome
Symptom relief CompletedThis study looked at whether a low-dose vaginal estrogen tablet could improve overactive bladder symptoms in menopausal women by changing the bacteria in their urine. Thirty women used the tablet daily for two weeks, then twice a week for 12 weeks. Researchers measured changes in…
Matched conditions: MENOPAUSE
Phase: PHASE4 • Sponsor: Mahidol University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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New hope for menopause brain fog: simple cognitive program shows promise
Symptom relief CompletedThis study tested a cognitive intervention to help manage 'brain fog'—memory and concentration problems—during menopause. It involved 33 women aged 40-60 who reported cognitive difficulties. The goal was to see if the program was feasible and acceptable, offering a non-hormonal o…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Could a brain steroid ease menopause depression?
Symptom relief CompletedThis study tested whether a natural substance called pregnenolone can help reduce depression in women going through menopause or perimenopause. 73 women took either pregnenolone or a placebo for several weeks. Researchers measured changes in mood, anxiety, thinking, and quality o…
Matched conditions: MENOPAUSE
Phase: PHASE1, PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Game on for better sleep: interactive training eases menopause symptoms
Symptom relief CompletedThis study tested whether interactive game-supported sleep hygiene training could improve sleep quality, menopausal symptoms, and quality of life in menopausal women. 82 women aged 40-60 with poor sleep took part. They received four sleep hygiene lessons paired with a digital gam…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Meryem Vural Şahin • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New light probe offers hope for menopause vaginal pain
Symptom relief CompletedThis study tested a new vaginal probe that uses special lights to treat vaginal atrophy in 25 postmenopausal women who had not been helped by other treatments. The probe aims to reduce pain and dryness by stimulating natural tissue repair. The main goal was to check safety and se…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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500 women test supplement for hot flashes and stress
Symptom relief CompletedThis study tested whether a dietary supplement called Radicle Revive can improve stress, sleep, and menopause-related issues in 500 perimenopausal women aged 40 and older. Participants took either the active supplement or a placebo for 6 weeks. The trial is complete, but results …
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Radicle Science • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can laughter ease menopause? study tests yoga for symptom relief
Symptom relief CompletedThis study tested whether laughter yoga can help manage menopause symptoms and improve quality of life. Researchers divided 120 postmenopausal women into two groups, with one group doing laughter yoga sessions. The goal was to see if this fun, low-cost activity could reduce commo…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Gut health boost? probiotic blend tested for menopause symptom relief
Symptom relief CompletedThis study tested whether a daily probiotic capsule containing three bacterial strains could improve quality of life and reduce menopause symptoms in 245 women aged 45-60 who were in perimenopause or early postmenopause. Participants took either the probiotic or a placebo for sev…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: AB Biotics, SA • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Can a simple injection ease menopause pain? new study investigates
Symptom relief CompletedThis small pilot study tested whether injecting a gel-like substance (hyaluronic acid) into the vaginal area could help menopausal women with pain during sex and vaginal dryness. Twenty women received the injections and were followed for 8 weeks. The main goal was to see if the v…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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New pill could cool menopause hot flashes without hormones
Symptom relief CompletedThis study tested an experimental drug called NOE-115 in 40 women aged 45 to 60 who have moderate to severe hot flashes due to menopause. The goal was to see if the drug is safe and can reduce symptoms. Participants took the drug for 4 weeks, and researchers tracked side effects …
Matched conditions: MENOPAUSE
Phase: PHASE2 • Sponsor: Noema Pharma AG • Aim: Symptom relief
Last updated Jun 26, 2026 15:48 UTC
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Menopause may weaken bladder and lungs, study hints
Knowledge-focused CompletedThis completed study looked at 28 postmenopausal women to see if bladder and sexual symptoms are linked to lung function and breathing muscle strength. Participants answered questionnaires and took breathing tests. The goal was to better understand these connections, not to test …
Matched conditions: MENOPAUSE
Sponsor: Halic University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can a Fast-Paced presentation style bust menopause myths?
Knowledge-focused CompletedThis study tested whether a quick, visual presentation style called Pecha Kucha works better than standard PowerPoint for teaching women about menopause. Five hundred women aged 30 to 65 who had never learned about menopause before took part. The goal was to see if the new method…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Tokat Gaziosmanpasa University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Can a simple supplement boost brain function in menopause?
Knowledge-focused CompletedThis study tested whether low doses of choline, a nutrient found in foods like eggs, can change brain activity in postmenopausal women. Twenty healthy women aged 50–65 received either 550 mg, 1100 mg of choline, or a placebo on separate days. Researchers used brain scans (fMRI) t…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Julie Dumas • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Exercise boosts fitness in menopausal women, small study finds
Knowledge-focused CompletedThis study looked at whether 24 sessions of moderate aerobic exercise could improve fitness in postmenopausal women who get short of breath easily. Researchers measured how well their hearts and lungs worked during exercise. The goal was to see if exercise training can help reduc…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University of Poitiers • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Menopause and skin: new study reveals hidden links
Knowledge-focused CompletedThis study looked at 100 women at different stages of menopause to see how skin aging in sun-exposed and non-exposed areas relates to hot flashes, mood, and sleep. Researchers measured skin wrinkles, color, elasticity, and moisture, and tracked sleep and symptoms at home for 30 d…
Matched conditions: MENOPAUSE
Sponsor: ChinaNorm • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Hormone therapy may improve fatty liver in menopause, small study suggests
Knowledge-focused CompletedThis study examined whether menopausal hormone therapy (MHT) can improve liver function and reduce fat buildup in the liver in postmenopausal women. 44 women were split into two groups: 22 received MHT and 22 did not. After 6 months, researchers measured liver enzymes, fat levels…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Ipek B. Ozcivit Erkan, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Menopause timing linked to mental health? new study investigates
Knowledge-focused CompletedThis study looked at 136 women to see if the age they entered menopause is linked to anxiety and depression. Researchers compared women with early menopause (before age 40) to those with natural menopause after 40. Participants filled out standard anxiety questionnaires during a …
Matched conditions: MENOPAUSE
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Could a single dose of choline boost brain activity in menopause?
Knowledge-focused CompletedThis study tested whether a single 1650 mg dose of choline, a nutrient found in foods like eggs and meat, affects brain activity in postmenopausal women. Thirty-eight healthy women aged 50–65 took either choline or a placebo and had their brains scanned with fMRI while doing a me…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: University of Vermont • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Brain scans reveal why menopause makes some women snappy
Knowledge-focused CompletedThis study involved 40 women in early menopause who reported increased irritability. Researchers gave them either estrogen patches or placebo patches to see how their brains reacted to hormone changes. The goal was to understand the brain mechanisms behind mood swings, not to tes…
Matched conditions: MENOPAUSE
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Your temperament may shape your menopause experience
Knowledge-focused CompletedThis study looked at whether a woman's natural temperament (like being more anxious or upbeat) is linked to how severe her menopause symptoms are. Researchers surveyed 105 women going through menopause using two standard questionnaires. The goal was simply to understand connectio…
Matched conditions: MENOPAUSE
Sponsor: Bagcilar Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Estrogen cream showdown: do custom formulas match up?
Knowledge-focused CompletedThis study looked at whether two specially made estrogen creams deliver similar amounts of the hormone into the blood. Eight postmenopausal women aged 45 to 65 used both creams, and researchers measured hormone levels after single and repeated use. The goal was to check quality, …
Matched conditions: MENOPAUSE
Phase: EARLY_PHASE1 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Hormone pellet study tracks estrogen levels for six months
Knowledge-focused CompletedThis study looked at how a 25-mg estradiol pellet, placed under the skin, releases estrogen over 24 weeks in 20 postmenopausal women. Researchers took many blood samples to measure hormone levels and understand the pellet's release pattern. The goal was to gather detailed informa…
Matched conditions: MENOPAUSE
Phase: NA • Sponsor: Science Valley Research Institute • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:23 UTC