Can garlic and enzymes make menopause hormones safer?
NCT ID NCT02618148
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding natural ingredients like garlic oil and nattokinase to standard hormone replacement therapy (HRT) could reduce the risk of blood clots in menopausal women. The trial involved 60 women divided into premenopausal and postmenopausal groups. Researchers measured how quickly estrogen levels rose to see if the combo was safer than HRT alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hormone replacement therapy (estradiol and progesterone) combined with garlic oil and nattokinase
What this could lead to
If successful, this could point toward a safer way to use hormone therapy for menopause symptoms by lowering the risk of blood clots.
What could go wrong
This is a small, early-phase study with only 60 participants, so results may not apply to everyone. The combination's safety and effectiveness need much larger trials to confirm.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Saigon Biopharma Company Limited
Ho Chi Minh City, 700000, Vietnam