New pill could cool menopause hot flashes without hormones
NCT ID NCT06385795
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested an experimental drug called NOE-115 in 40 women aged 45 to 60 who have moderate to severe hot flashes due to menopause. The goal was to see if the drug is safe and can reduce symptoms. Participants took the drug for 4 weeks, and researchers tracked side effects and how well it worked.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NOE-115
What this could lead to
If successful, this could point toward a new non-hormonal treatment option for hot flashes during menopause.
What could go wrong
This is a small, early-phase trial with only 40 women and no placebo group, so results may not be conclusive or apply to everyone. Side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Noema PMM-201 Site #101
Atlanta, Georgia, 30030, United States
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Noema PMM-201 Site #102
Jacksonville, Florida, 32256, United States
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Noema PMM-201 Site #103
Seattle, Washington, 98105, United States
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Noema PMM-201 Site #104
San Diego, California, 92111, United States
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Noema PMM-201 Site #106
Las Vegas, Nevada, 89106, United States