Vaginal estrogen may ease bladder troubles by altering urine microbiome

NCT ID NCT06780163

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether a low-dose vaginal estrogen tablet could improve overactive bladder symptoms in menopausal women by changing the bacteria in their urine. Thirty women used the tablet daily for two weeks, then twice a week for 12 weeks. Researchers measured changes in Lactobacillus levels and other urine bacteria, and linked those changes to symptom improvement.

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Conditions

The condition(s) this trial relates to.

overactive bladder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Medicine Ramathibodi Hospital, Mahidol University

    Bangkok, 10400, Thailand